Experimental Neurology
November 1, 2021
Matteo Marti, Giuseppe Talani, Cristina Miliano et al.
6 citations
Methoxetamine (MXE) is a dissociative substance of the arylcyclohexylamine class that has been present on the designer drug market as a ketamine-substitute since 2010. We have previously shown that MXE (i) possesses ketamine-like discriminative and positive rewarding effects in rats, (ii) affects brain processing involved in cognition and emotional responses, (iii) causes long-lasting...
Neuroscience of Consciousness
November 1, 2021
Andrea I. Luppi, Pedro A. M. Mediano, Fernando E. Rosas et al.
42 citations
Abstract A central question in neuroscience concerns the relationship between consciousness and its physical substrate. Here, we argue that a richer characterization of consciousness can be obtained by viewing it as constituted of distinct information-theoretic elements. In other words, we propose a shift from quantification of consciousness—viewed as integrated information—to its...
Frontiers in Psychology
October 29, 2021
Masaru Tanaka, Ryoichi Nakashima, Kentaro Hiromitsu et al.
7 citations
Mindfulness meditation is increasingly used for clinical treatment and to improve well-being. One of the most fundamental benefits of mindfulness meditation is now considered as enhanced attentional control. Mindfulness meditation is a complex technique but most of its variants consist of a combination of two types of basic meditation practice: focused attention meditation (FAM) and open...
Alcoholism & Drug Abuse Weekly
October 29, 2021
Alison Knopf
Most patients with substance use disorder (SUD) also have anxiety, and many have post‐traumatic stress disorder (PTSD), using drugs or alcohol to self‐medicate (although not effectively). What happens with PTSD occurs in the amygdala, explained George Koob, Ph.D., director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA), in an interview with ADAW last week. The emotional part...
Frontiers in Psychology
October 28, 2021
Bernd Brabec de Mori
15 citations
During the last decades, ayahuasca gained much popularity among non-Indigenous and out-of-Amazonia based populations. In popular culture, it has been advertised as a natural remedy that was discovered by Indigenous peoples ante millennia and that has been used for shamanic healing of all kinds of ailments. This “neo-shamanic,” and often recreational, use of ayahuasca, however, has to be...
Frontiers in Pharmacology
October 27, 2021
Nafsika Poulia, Foteini Delis, Charalampos Brakatselos et al.
Clinical evidence and experimental studies have shown the psychotomimetic properties induced by ketamine. Moreover, acute or chronic ketamine (KET) administration has been widely used for modeling schizophrenia-like symptomatology and pathophysiology. Several studies have reported the antipsychotic potential of cannabidiol (CBD), while there is limited information on the cannabidiol effect on...
Philosophy and the Mind Sciences
October 26, 2021
Chen Song
Structure shapes function. Understanding what is structurally special about the brain that allows it to generate consciousness remains a fundamental scientific challenge. Recently, advances in brain imaging techniques have made it possible to measure the structure of human brain, from the morphology of neurons and neuronal connections to the gross anatomy of brain regions, in-vivo and...
ACS Medicinal Chemistry Letters
October 21, 2021
Robert B. Kargbo
15 citations
ADVERTISEMENT RETURN TO ISSUEPREVPatent HighlightNEXT5-MeO-DMT: Potential Use of Psychedelic-Induced Experiences in the Treatment of Psychological DisordersRobert B. Kargbo*Robert B. KargboUsona Institute, 277 Granada Drive, San Luis Obispo, California 93401-7337, United States*Email: [email protected]More by Robert B. Kargbohttps://orcid.org/0000-0002-5539-6343Cite this: ACS Med. Chem. Lett....
Archiv Euromedica
October 17, 2021
Lavinia-Alexandra Moroianu, Marius Moroianu, Anamaria Ciubară
3 citations
Marijuana is the most widely used psychoactive substance after coffee and it is used for both medical and recreational purposes. It has been known since ancient times and it seems to have been part of the mixture that was put in the pipe of “peace” by Native Americans. Marijuana is psychically addictive, but in its case, there is no physical addiction as in the case of high-risk drugs (heroin)...
Frontiers in Psychology
October 12, 2021
Nava Levit‐binnun, Keren Arbel, Dusana Dorjee
When considering the numerous mindfulness-based and mindfulness-informed programs that have flourished in the past decades it is not always clear that they all refer to the same "mindfulness. " To facilitate more clarity and precision in describing, researching and teaching mindfulness in the secular settings, we propose a classification framework of mindfulness practices, intentions behind...