Psychiatry Research2023Ricci Valerio, Ceci Franca, Di Carlo Francesco et al.
BACKGROUND Natural Cannabis (NC) and Synthetic Cannabinoids (SCs) use can increase the risk of developing psychotic disorders and exacerbate their course. AIMS To examine the differences between psychoses not associated with cannabis use and those associated with NC and SCs use, evaluating psychotic symptoms, global functioning, dissociative symptoms and suicidal ideation. METHODS The sample of...
N,N-dimethyltryptamine (DMT) belongs to a class of drugs known as serotonergic psychedelics, which produce profound shifts in consciousness by dramatically altering perception and causing hallucinatory phenomena. In humans, DMT has a rapid onset and the effects, which include feelings of dissociation from external reality, entering into an ‘otherworldly dimension’, and intense internal visual...
Assess changes in symptoms of anxiety, depression, and psychosocial or spiritual distress before and after ketamine-assisted psychotherapy (KAP) in individuals with problematic substance use (PSU). A retrospective chart review was performed on participant data from two five-year prospective outcomes studies: the AIMS Medical Outcomes Study (AMOS) and the AIMS Cancer Outcomes Study (ACOS). The...
Hallucinogens are a broad category of substances encompassing drugs with diverse pharmacological, phenomenological, and adverse effects. In this chapter, the focus is on disorders caused by and exacerbated by two classes of hallucinogens. These are classic psychedelics (drugs including LSD and psilocybin that exert subjective effects principally by 5HT_2A agonism) and the substituted...
The article is devoted to the soteriological practice of the schools of Chinese Buddhism -the practice of meditation, its relationship with philosophy.The significance of the theory of two truths revealing the essence of the unity of philosophy and meditation is shown.On the example of the meditation practice of the Tiantai School, known as zhi guan, an explication of the relationship between...
Intoxication in the Ancient Greek and Roman World considers the psychotropic plants used in the ancient world and ancient attitudes towards intoxication. Alan Sumler surveys primary Greek and Roman sources for noteworthy mentions of ancient intoxicants like hellebore, mandrake, deadly nightshade, thorn apple, opium poppy, cannabis, wine, and other substances and reveals how psychoactive drugs...
The purpose of this article is to review various opinions of Soviet scientists about mental health of shamans. The task of this paper is to analyse a wide range of Soviet sources on shamanism, identify their attitude to “shamanic madness” and possible reasons for its formation, and compare positions of different authors on the subject. The following methods were used: comparative, causal...
Psychedelics might be the oldest psychoactive agents known to be used for inducing religious or mystical experiences. Their strong psychoactive effect was discovered accidentally in 1943 after the synthesis of Lysergic acid diethylamide (LSD) in 1937. These drugs became a mainstream area of research following the synthesis of LSD; however, several political and social factors led to their ban...
INTRODUCTION: Psychotic disorders are considered chronic mental health issues. Although it has been demonstrated that these disorders can present with a wide range of symptoms, pharmacological treatment is based on the use of typical and atypical antipsychotics, whose main mechanism of action is dopaminergic blockade, limiting their effect to the improvement of positive symptoms, without...
Since their introduction to mainstream culture and medicine in the middle of the 20th century, psychedelic substances have been investigated for their therapeutic potential. Research on psychedelic therapy, or the use of moderate-to-large doses of psychedelics in the context of therapy, indicates that psychedelics have great potential to treat disorders such as depression, addiction, and...