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Daniel Martins

4 papers in the library · 91 citations · publishing 2017-2024

Papers

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Mechanistic Insights into the Neurotoxicity of 2,5-Dimethoxyphenethylamines (2C) and Corresponding N-(2-methoxybenzyl)phenethylamine (NBOMe) Drugs.

Journal of Xenobiotics June 5, 2024 Eva Gil-Martins, Fernando Cagide-Fagín, Daniel Martins et al. 2 citations

Substituted phenethylamines including 2C (2,5-dimethoxyphenethylamines) and NBOMe (N-(2-methoxybenzyl)phenethylamines) drugs are potent psychoactive substances with little to no knowledge available on their toxicity. In the present in vitro study, we explored the mechanisms underlying the neurotoxicity of six substituted phenethylamines: 2C-T-2, 2C-T-4, 2C-T-7 and their corresponding NBOMes....

Bonding to Psychedelics: Synthesis of Molecularly Imprinted Polymers Targeting 4-Bromo-2,5-dimethoxyphenethylamine (2C-B)

Applied Sciences Switzerland February 1, 2024 Daniel Martins, Carlos Fernandes, Ricardo F. Mendes et al.

The increasing interest in utilizing psychedelics for therapeutic purposes demands the development of tools capable of efficiently monitoring and accurately identifying these substances, thereby supporting medical interventions. 4-Bromo-2,5-dimethoxyphenethylamine (2C-B) has gained significant popularity as one of the most widely used psychedelic compounds in non-medical settings. In this...

Unraveling the In Vitro Toxicity Profile of Psychedelic 2C Phenethylamines and Their N-Benzylphenethylamine (NBOMe) Analogues

Pharmaceuticals August 15, 2023 Daniel Martins, Eva Gil-Martins, Fernando Cagide et al. 13 citations

Mescaline derivative (2C phenethylamines) drugs have been modified by the introduction of a N-2-methoxybenzyl group to originate a new series of compounds with recognized and potent psychedelic effects, the NBOMe-drugs. Although they are prevalent in unregulated drug markets, their toxicity profile is still poorly understood, despite several reports highlighting cases of acute intoxication,...

The detection and prevention of unintentional consumption of DOx and 25x‐NBOMe at Portugal's Boom Festival

Human Psychopharmacology Clinical and Experimental May 1, 2017 Daniel Martins, Monica J Barratt, Cristiana Vale Pires et al. 76 citations

Abstract Objective This paper describes the misrepresentation of LSD at Portugal's Boom Festival 2014 and the prevention of unintentional consumption of DOx and 25x‐NBOMe among LSD consumers attending a drug‐checking service. Methods Two hundred forty‐five drug samples expected to contain LSD were submitted to the drug‐checking service for chemical analysis. One hundred ten post‐test...