Biological researchSeptember 11, 2026Lidia Szwajkowska‐Michałek, Małgorzata Graczyk, Anna Przybylska‐Balcerek et al.
Abstract Background This study analyzed the content and composition of phenolic compounds, flavonoids, coumarins, pigments, and neuroactive secondary metabolites in fly agaric ( Amanita muscaria ) fruiting bodies collected in August and September 2022 and 2023 from two sites: under pine trees and under birch trees in the Wielkopolska region. A total of 15 phenolic compounds, as well as groups...
Background 3,4-Methylenedioxymethamphetamine (MDMA) is associated with distinctive prosocial and empathogenic effects, yet the consistency and scope of its impact on social cognition in humans remain unclear. Although numerous placebo-controlled studies have examined MDMA’s acute social effects, findings vary widely across subjective and behavioural domains. Methods We conducted a systematic...
Journal La BisecomanSeptember 11, 2026La Himmah Il Princess Choris, M. Shoim M. Shoim
The rapid advancement of Artificial Intelligence (AI), particularly Large Language Models (LLMs) and algorithmic recommendation systems, has fundamentally transformed how human beings produce, distribute, and consume information. Yet contemporary debates surrounding AI remain trapped between two dominant narratives: technological optimism, which views AI as a productivity accelerator, and...
Ketamine and subcallosal cingulate (SCC) deep brain stimulation (DBS) have each shown antidepressant effects in treatment-resistant depression, yet how ketamine modulates SCC physiology during chronic stimulation remains poorly understood. We analyzed 5,907 hours of bilateral SCC sensing, 485 participant-triggered recordings across 193 days, 47 ketamine dosing episodes, and an in-clinic...
NeuropharmacologySeptember 11, 2026Laura Rullo, Loredana Maria Losapio, Hela Mrizak et al.
Alcohol use disorder (AUD) represents a major public health challenge, with current pharmacological and psychotherapeutic treatments showing limited efficacy. Recent clinical evidence suggests that MDMA-assisted psychotherapy may be effective for AUD, although concerns remain regarding its safety and potential for recreational use. This study investigated the effects of MDMA administration on...
Whether artificial intelligence (AI) can be conscious is usually treated as a question for philosophers of mind, and the replacement of human labor by AI as a question for economists. This article argues that the two questions are entangled and that their separation is an artifact of the epistemology of modern economics. In a documented corpus of 100 Scopus-indexed records on AI, labor, and...
medRxivSeptember 10, 2026Mori Krantz, Mark C. Haigney, Mary Ross Southworth et al.
preprint
Background: Several Schedule I substances have demonstrated potential benefits for refractory psychiatric conditions and addiction. Some have been legalized at the state level, while others like kratom (mitragynine) are available over-the-counter in some states and illegal in others. A recent presidential executive order directs certain federal agencies to accelerate development and facilitate...
This study examines how lay women engage with, adapt, and transmit the heart-mind esoteric Buddhist tradition known as Foxin Jing () in contemporary China. Previous scholarship on Chinese esoteric Buddhism has predominantly focused on issues related to legitimacy, lineage, institutional power, and master-disciple relations. However, there has been a relative lack of focus on the role played by...
Mindfulness practice and metacognition each support adaptive cognition by cultivating present-moment, nonjudgmental awareness and the capacity to monitor and regulate one’s mental processes. The present thesis tested whether two brief and common mindfulness inductions (focused attention and open monitoring) differentially influenced construal level (concrete vs. abstract) as measured on the...
Caffeine is widely studied as a facilitator of externally directed cognition, yet comparatively little is known about its effects on spontaneous cognition when external behavioural demands are weak. This paper proposes that caffeine can induce a distinctive state of ego-confrontation during rest. Acute caffeine reduces posterior default mode network (DMN) coherence while increasing DMN temporal...