4 results for "Meta-analysis: What did research on Psilocybin find in August 2026?"

The subtle science: a systematic review of psilocybin magic mushroom and truffle microdosing

Frontiers in Psychiatry August 19, 2026 Jeni Page, Alexandra Moore, Bridget E. Hawkins et al.

IntroductionMicrodosing psilocybin magic mushrooms (MM) and truffles has grown in popularity, but the evidence supporting reported benefits remains poorly characterized. The purpose of this systematic review was to synthesize the existing literature on microdosing psilocybin MM and truffles in adults to determine reported health effects and perceived benefits, motivations for use, dosing...

DOI: 10.3389/fpsyt.2026.1866881 Full text Magic mushrooms Microdosing Psilocybin Psychedelic substances +1

Psilocybin-assisted therapy for major depressive disorder: Perspective from meta-analysis.

Journal of Affective Disorders August 1, 2026 Taro Kishi, Kenji Sakuma, Masakazu Hatano et al.

This systematic review and meta-analysis of six randomized controlled trials aimed to investigate the temporal changes in the efficacy and safety of psilocybin treatment for major depressive disorder (MDD). Separate meta-analyses were conducted for standard-dose psilocybin (25 mg/session, or 20-30 mg/70 kg/session) and low-dose psilocybin (10 mg/session or 15.05 mg/70 kg/session) subgroups....

DOI: 10.1016/j.jad.2026.121675 Full text Depression Psilocybin Meta-analysis Randomized controlled trial +1

The role of therapeutic alliance in psilocybin treatment for treatment-resistant depression: A post hoc path analysis.

Journal of Affective Disorders August 1, 2026 Guy M. Goodwin, Scott T Aaronson, Oscar Alvarez et al. 2 citations

The contribution of patient support to psilocybin's antidepressant effects remains uncertain. Relationships between therapeutic alliance (Scale to Assess Therapeutic Relationship-Patient version; STAR-P), psychedelic experience (Five-Dimensional Altered States of Consciousness Questionnaire and Emotional Breakthrough Inventory; 5D-ASC and EBI) and clinical outcomes (Montgomery-Åsberg Depression...

DOI: 10.1016/j.jad.2026.121662 Full text Psilocybin Treatment-resistant depression Psychedelic experience Psychological support +1

Current status and future prospects of research on psilocybin's regulation of neurotransmitters and their receptors related to the pathogenesis of tinnitus.

Hearing research August 1, 2026 Shuhan Lu, Zhixin Zhang, Xinmiao Xue et al.

Subjective tinnitus is a common auditory disorder characterised by the subjective perception of noise in the absence of external sound sources. Its prevalence has been rising annually due to noise exposure, medication misuse, and population ageing. Current tinnitus treatments employ antidepressants, anticonvulsants, and vasodilators, yet most demonstrate limited efficacy with significant side...

DOI: 10.1016/j.heares.2026.109701 Full text 5-ht2a receptor Psilocybin Dopamine Gaba +2