[Case report: the psychotic-mystical effects related to an unaware use of Salvia divinorum.].
Marcella Dedomenici, Vincenzo Arienti, Filippo Mazzoni, Pierluigi Politi, Giovanni Migliarese
Recenti progressi in medicina October 1, 2022 DOI: 10.1701/3888.38708 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | Patient in Vigevano, Italy |
| Intervention | Brexiprazole |
| Topics | Salvia divinorum |
| Keywords | Designer drugs Synthetic drugs Novel psychoactive substances Emerging drugs Nps psychosis Salvia psychosis Toxic psychosis Substance-related psychiatric disorder Psychiatric condition Mental illness Altered mental state Salvia divinorum salvia Psychoactive plant Hallucinogen Dissociative Natural psychoactive substance Brexiprazole antipsychotic Medication Pharmacotherapy Drug treatment Atypical antipsychotic |
| Citations | 1 |
| Key findings | A patient with Salvia divinorum-induced psychosis showed excellent response to brexiprazole after two other antipsychotics failed. |
Abstract
It's well known that exotoxicosis can originate various psychiatric clinical pictures. The psychic impact of "classic" substances of abuse is well known and easily detectable with the usual methods of examination. In the last years new psychoactive substances (NPS) are spreading worldwide, determining not easily recognizable situations, with a significant clinical and organizational impact on psychiatry. In this case report, we present a clinical picture treated in hospital and outpatient settings in Vigevano (Pavia - Italy) and characterized by a psychotic onset secondary to an unaware use of Salvia divinorum. After the failure of two psychopharmacological treatment, the patient showed an excellent response to brexiprazole, with substantial restitutio ad integrum in the absence of significant side effects.
Comparable studies
Other case reports and case series on salvia divinorum, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Salvia divinorum: an hallucinogenic mint which might become a new recreational drug in Switzerland. Salvia divinorum specimens seized in Switzerland | 2000 | Case study | |
| Antidepressant Effects of the Herb Salvia Divinorum: A Case Report 26-year-old woman with history of depression | 2001 | Case study | n = 1 |
| Chemogenomics knowledgebase and systems pharmacology for hallucinogen target identification-Salvinorin A as a case study. | 2016 | Database construction with computational prediction and case study | |
| A Report of Nausea and Vomiting with Discontinuation of Chronic Use of Salvia divinorum 51-year-old Caucasian woman | 2015 | Case study | n = 1 |
| Prolonged hallucinations and dissociative self mutilation following use ofSalvia divinorumin a bipolar adolescent girl A 17-year-old girl with bipolar disorder | 2010 | Case study | n = 1 |