Prolonged hallucinations and dissociative self mutilation following use ofSalvia divinorumin a bipolar adolescent girl
Jean‐Jacques Breton, Christophe Huỳnh, Sylvie Raymond, Réal Labelle, Nicolas Bonnet, David B. Cohen, J.-M. Guilé
Journal of Substance Use April 1, 2010 DOI: 10.3109/14659890903060167 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A 17-year-old girl with bipolar disorder |
| Topics | Salvia divinorum |
| Citations | 6 |
| Key findings | The case suggests that recreational use of Salvia divinorum can trigger prolonged hallucinations and dissociative states with self-destructive behavior in individuals with bipolar disorder, indicating potential psychiatric risks in vulnerable populations. |
Abstract
The case of a bipolar 17-year-old girl who developed prolonged vivid hallucinations and a dissociative state involving self-destructive behaviour following the use of Salvia divinorum is presented. The herb has mostly short-term (10–15 min) hallucinogenic properties. Salvatorin A, the main active compound, is a highly selective agonist of the kappa-opioid receptor. The plant is available at tobacco or other specialized stores in many countries such as France, UK, Canada, and USA, where it is legal. The clinical case reported in this article suggests that the recreational use of Salvia divinorum may result in serious psychiatric consequences in vulnerable individuals.
Comparable studies
Other case reports and case series on salvia divinorum, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Salvia divinorum: an hallucinogenic mint which might become a new recreational drug in Switzerland. Salvia divinorum specimens seized in Switzerland | 2000 | Case study | |
| Antidepressant Effects of the Herb Salvia Divinorum: A Case Report 26-year-old woman with history of depression | 2001 | Case study | n = 1 |
| Chemogenomics knowledgebase and systems pharmacology for hallucinogen target identification-Salvinorin A as a case study. | 2016 | Database construction with computational prediction and case study | |
| A Report of Nausea and Vomiting with Discontinuation of Chronic Use of Salvia divinorum 51-year-old Caucasian woman | 2015 | Case study | n = 1 |
| Case series: Salvia divinorum as a potential addictive hallucinogen. Patients presenting with an enduring and pervasive pattern of salvia use | 2018 | Case study | n = 2 |
Citations in the library
Cited by 3
- Lack of effect of sublingual salvinorin A, a naturally occurring kappa opioid, in humans: a placebo-controlled trial. Psychopharmacology April 1, 2011
- Recent national trends in Salvia divinorum use and substance-use disorders among recent and former Salvia divinorum users compared with nonusers. Substance Abuse and Rehabilitation April 1, 2011
- Epidemiology of adolescent Salvia divinorum use in Canada. Drug and Alcohol Dependence February 1, 2013
Cites 5
- Opioid receptors and legal highs:Salvia divinorumand Kratom Clinical Toxicology 2008
- Pattern of use and subjective effects of Salvia divinorum among recreational users. Drug and Alcohol Dependence November 8, 2006
- Salvia divinorum and salvinorin A: an update on pharmacology and analytical methodology. Planta Medica August 1, 2007
- College student use of Salvia divinorum. Drug and Alcohol Dependence April 1, 2008
- Subjective effects of Salvia divinorum. Journal of Psychoactive Drugs June 1, 2007