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Effects of a Brief Inpatient Mindfulness‐Based Stress Reduction Program on Psychological Distress and Marital Satisfaction in High‐Risk Pregnancy: A Randomized Controlled Trial

Solmaz Heydarifard, Faezeh Safaralinezhad, Atefeh Safaralinezhad

Health science reports September 23, 2026 DOI: 10.1002/hsr2.73154 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Sample size 57
Population Pregnant women at 24-28 weeks' gestation hospitalized for premature rupture of membranes
Duration 8-week intervention; assessments at baseline, post-intervention, and 4-week postpartum follow-up
Measures Mental Health Inventory (MHI-28) distress subscale, Five Facet Mindfulness Questionnaire (FFMQ), Kansas Marital Satisfaction Scale (KMSS)
Topics Meditation
Keywords High‐risk pregnancy Marital satisfaction Mindfulness‐based stress reduction Perinatal mental health Randomized controlled trial
Key findings In hospitalized women with high-risk pregnancies, an 8-week brief inpatient MBSR program produced sustained improvements in mindfulness and marital satisfaction and significant reductions in anxiety and depressive symptoms compared with treatment-as-usual, with significant time-by-group interactions for all outcomes (all p < 0.001). The authors conclude that brief inpatient MBSR may reduce psychological distress and improve marital satisfaction in this population.

Abstract

ABSTRACT Objective Hospitalized women with high‐risk pregnancies are particularly vulnerable to psychological distress and relational strain. This randomized controlled trial aimed to evaluate the effectiveness of a brief inpatient mindfulness‐based stress reduction (MBSR) program in improving psychological distress and marital satisfaction.

Methods: Fifty‐seven pregnant women (24–28 weeks' gestation) hospitalized for premature rupture of membranes were randomized to either an 8‐week brief MBSR program or treatment‐as‐usual. Fifty‐three participants completed the study. Outcomes included psychological distress assessed by the distress subscale of the Mental Health Inventory (MHI‐28), mindfulness measured by the Five Facet Mindfulness Questionnaire (FFMQ), and marital satisfaction assessed by the Kansas Marital Satisfaction Scale (KMSS), assessed at baseline, post‐intervention, and 4‐week postpartum follow‐up. Repeated‐measures ANOVA with Greenhouse–Geisser correction was performed.

Results: Significant time × group interactions were observed for mindfulness, anxiety, depression, and marital satisfaction (all p < 0.001). Participants in the intervention group showed sustained improvements in mindfulness and marital satisfaction and significant reductions in anxiety and depressive symptoms compared with controls.

Conclusion: A brief inpatient MBSR program may reduce psychological distress and improve marital satisfaction among hospitalized women with high‐risk pregnancies. Larger multicenter trials with extended follow‐up are warranted.

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