Skip to content

Impact of mindfulness-based and health self-management interventions on mindfulness, self-compassion, and physical activity in older adults with subjective cognitive decline: A secondary analysis of the SCD-Well randomized controlled trial.

Ylenia D'elia, Tim Whitfield, Marco Schlosser, Antoine Lutz, Thorsten Barnhofer, Gaël Chételat, Natalie L. Marchant, Julie Gonneaud, Olga Klimecki

Alzheimer S and Dementia Diagnosis Assessment and Disease Monitoring 2024 DOI: 10.1002/dad2.12558 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Multicenter, observer-blind, randomized, controlled, superiority trial Peer reviewed
Sample size 347
Population Older adults with subjective cognitive decline (SCD) recruited from memory clinics in four European sites; mean age 72.7 years, 64.6% women
Interventions Caring mindfulness-based approach for seniors (CMBAS) Health self-management program (HSMP)
Duration 8-week intervention; follow-up visit at 24 weeks
Topics Meditation
Keywords Alzheimer's disease Aging Dementia Non‐pharmacological interventions Physical activity Self‐compassion
Key findings The caring mindfulness-based approach for seniors (CMBAS) increased self-compassion within-group from baseline to post-intervention and both within- and between-group to the 24-week follow-up, while the health self-management program (HSMP) increased physical activity within- and between-group from baseline to post-intervention and to follow-up. The authors conclude that non-pharmacological interventions can differentially promote modifiable factors linked to healthy aging in older adults with SCD.

Abstract

Older adults experiencing subjective cognitive decline (SCD) have a higher risk of dementia. Reducing this risk through behavioral interventions, which can increase emotional well-being (mindfulness and compassion) and physical activity, is crucial in SCD. SCD-Well is a multicenter, observer-blind, randomized, controlled, superiority trial. Three hundred forty-seven participants (mean [standard deviation] age: 72.7 [6.9] years; 64.6% women) were recruited from memory clinics in four European sites to assess the impact of an 8-week caring mindfulness-based approach for seniors (CMBAS) and a health self-management program (HSMP) on mindfulness, self-compassion, and physical activity. CMBAS showed a significant within-group increase in self-compassion from baseline to post-intervention and both a within- and between-group increase to follow-up visit (24 weeks). HSMP showed a significant within- and between-group increase in physical activity from baseline to post-intervention and to follow-up visit. Non-pharmacological interventions can differentially promote modifiable factors linked to healthy aging in older adults with SCD.

Comparable studies

Other randomized controlled trials on meditation, most cited first.

Study Year Design Participants
Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment 2003 Randomized controlled trial n = 41
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults 2008 Randomized controlled trial n = 139
Short-term meditation training improves attention and self-regulation Undergraduate Chinese students 2007 Randomized controlled trial n = 40
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

Citations in the library

Explore topics