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Effects of Mindfulness-Based Stress Reduction Intervention on Psychological Well-being and Quality of Life: Is Increased Mindfulness Indeed the Mechanism?

Ivan Nyklíček, Karlijn F. Kuijpers

Annals of Behavioral Medicine June 1, 2008 DOI: 10.1007/s12160-008-9030-2 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Sample size 60
Population Community adults with symptoms of distress
Intervention Mindfulness-based stress reduction
Topics Meditation
Keywords Mindfulness-based stress reduction Randomized controlled trial Clinical psychology Intervention counseling Health psychology Analysis of variance Distress Psychotherapist Public health
Citations 535
Post-publication review 1 comment on PubPeer (opens in new tab) · last active August 2016
Key findings MBSR significantly reduced perceived stress and vital exhaustion and increased positive affect, quality of life, and mindfulness; increased mindfulness may partially mediate these effects.

Abstract

Background: Although several studies have reported positive effects of mindfulness-based stress reduction (MBSR) intervention on psychological well-being, it is not known whether these effects are attributable to a change in mindfulness.

Purpose: The aim of this study is to compare the effects of MBSR to a waiting-list control condition in a randomized controlled trial while examining potentially mediating effects of mindfulness.

Methods: Forty women and 20 men from the community with symptoms of distress (mean age 43.6 years, SD = 10.1) were randomized into a group receiving MBSR or a waiting-list control group. Before and after the intervention period, questionnaires were completed on psychological well-being, quality of life, and mindfulness.

Results: Repeated measures multiple analysis of variance (MANCOVAs) showed that, compared with the control group, the intervention resulted in significantly stronger reductions of perceived stress (p = 0.016) and vital exhaustion (p = 0.001) and stronger elevations of positive affect (p = 0.006), quality of life (p = .009), as well as mindfulness (p = 0.001). When mindfulness was included as a covariate in the MANCOVA, the group effects on perceived stress and quality of life were reduced to nonsignificance.

Conclusion: Increased mindfulness may, at least partially, mediate the positive effects of mindfulness-based stress reduction intervention.

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