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DMT, Madness, and Healing: Psychosis Model, Therapy Model, and Their Relations to Mystical Experiences and Positive Emotionality

Isabel Wießner, Marcelo Falchi-Carvalho, Sophie Laborde, Handersson Barros, Raynara Bolcont, Melanie Medina, Daniel C Mograbi, Nicole Galvão-Coelho, Fernanda Palhano-Fontes, Draulio B Araujo

Research Square May 20, 2026 preprint DOI: 10.21203/rs.3.rs-9640916/v1 (opens in new tab)

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Study at a glance

AI-extracted from the abstract

Characteristics	Theoretical or philosophical paper
Topics	DMT Mystical experience
Key points	Argues that DMT experiences can model psychosis or serve as therapy depending on context, and that mystical experiences and positive emotionality are key to their therapeutic potential.

Abstract

DMT, Madness, and Healing: Psychosis Model, Therapy Model, and Their Relations to Mystical Experiences and Positive Emotionality