DMT, Madness, and Healing: Psychosis Model, Therapy Model, and Their Relations to Mystical Experiences and Positive Emotionality
Isabel Wießner, Marcelo Falchi-Carvalho, Sophie Laborde, Handersson Barros, Raynara Bolcont, Melanie Medina, Daniel C Mograbi, Nicole Galvão-Coelho, Fernanda Palhano-Fontes, Draulio B Araujo
Research Square May 20, 2026 DOI: 10.21203/rs.3.rs-9640916/v1 (opens in new tab)
Summary
AI-generated from the abstractThe paper explores the relationships among DMT-induced experiences, psychosis, healing, mystical experiences, and positive emotionality. It examines how DMT can serve as a model for psychosis and as a therapeutic tool, while also considering the overlap between these models and mystical experiences. The authors discuss the potential for DMT to induce states resembling psychosis but also to facilitate healing and positive emotional outcomes, suggesting that the context and set and setting are crucial in determining whether the experience leads to distress or well-being.
Study at a glance
| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Key finding | Argues that DMT experiences can model psychosis or serve as therapy depending on context, and that mystical experiences and positive emotionality are key to their therapeutic potential. |
Abstract
DMT, Madness, and Healing: Psychosis Model, Therapy Model, and Their Relations to Mystical Experiences and Positive Emotionality