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The Effects of some Hallucinogens on Aggressiveness of Mice and Rats

W Rewerski, Wojciech Kostowski, T Piechocki, M. Rylski

Pharmacology 1971 DOI: 10.1159/000136205 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Experimental study Peer reviewed
Population Isolated mice and rats
Interventions LSD mescaline Sernyl
Topics Mescaline
Keywords Hallucinogen Pharmacology Psychotomimetic
Citations 19
Key findings Mescaline strongly reduced aggressiveness in mice but not in rats, while LSD decreased aggressiveness in mice and Sernyl had dose-dependent effects on mouse aggression.

Abstract

The action of LSD, mescaline and Sernyl® onthe aggressiveness of isolated mice and killing reaction ofrats was investigated. At some dose range, LSD decreased the aggressiveness on isolation time. Mescaline was a strong in mice but not in rats whileSernyl slightly decreased the killing reaction and decreasedor increased the aggressiveness of mice according to dose level.

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