Empirical Dimensions of LSD-25 Reaction
Archives of General Psychiatry May 1, 1964 DOI: 10.1001/archpsyc.1964.01720230031004 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Empirical study Peer reviewed |
|---|---|
| Sample size | 74 |
| Population | Male prisoners |
| Intervention | LSD-25 |
| Dose | 1 mcg/kg |
| Topics | LSD |
| Keywords | Cognitive psychology |
| Citations | 8 |
| Key points | Subjective reactions to LSD-25 can be empirically differentiated into major dimensions, contrasting with prior a priori clinical groupings. |
Abstract
There has been, thus far, virtually no exploration of anempiricalbasis of the patterning of subjective reactions to lysergic acid diethylamide (LSD-25). Previous studies have been limited to general descriptions of the drug's effects, and the rare attempts to group the various specific effects have been based on a priori clinical concepts1(reviewed elsewhere). Furthermore, the relationships between a given LSD-25 reaction and the personalities of the individuals who manifest that reaction have been neglected. This report presents data bearing on these unexplored areas. The present attempt to differentiate empirically major dimensions of the LSD-25 reaction may be contrasted with previous studies which have presented clinical and, to some extent, systematic summaries of the separate aspects of the drug reaction. Only Salvatore and Hyde3and our own previous report1were concerned with clusters of reactions, and