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Behavioral Effects of Lysergic Acid Diethylamide (LSD-25)

Seymour Wapner

A M A Archives of General Psychiatry October 1, 1959 DOI: 10.1001/archpsyc.1959.03590040087008 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Experimental study Peer reviewed
Intervention LSD-25
Topics LSD
Keywords Space punctuation Developmental psychology Biochemistry
Citations 12
Key findings The paper examines the apparent horizon as a dimension of spatial organization under various test conditions, including the effects of LSD-25, but does not report a specific finding.

Abstract

The behavioral effects of lysergic acid diethylamide (LSD-25) have been studied programmatically in the Clark Laboratories, utilizing the framework of organismic and developmental theory. In the course of testing some of the implications of these theoretical positions, a number of situations have been developed to study space localization. This paper involves the situation dealing with the so-called apparent horizon, i. e., that point in space perceived to be at eye level. This dimension of spatial organization has been studied extensively under various test conditions, e. g., under conditions of success and failure,3and under conditions of energizing and tranquilizing drugs,1and for various groups: depressed manic-depressive, and elated manic-depressive groups2; children of various ages,4etc. Of particular pertinence to the present paper is a developmental study using children of ages ranging from 6 to 20 years.4In that

Comparable studies

Other experimental studies on LSD, most cited first.

Study Year Design Participants
Neural correlates of the LSD experience revealed by multimodal neuroimaging. Human participants 2016 Experimental study
Crystal structure of an LSD-bound human serotonin receptor 2017 Experimental study with structural biology and molecular dynamics simulations
Lysergic Acid Diethylamide: Sensitive Neuronal Units in the Midbrain Raphe Midbrain neurons containing serotonin 1968 Experimental study
Connectome-harmonic decomposition of human brain activity reveals dynamical repertoire re-organization under LSD. Human brain 2017 Experimental study
LSD-Assisted Psychotherapy in Patients with Terminal Cancer Cancer patients 1973 Experimental study n = 60

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