Effects of LSD-25 on Tests of Personality
Journal of Mental Science October 1, 1958 DOI: 10.1192/bjp.104.437.1226 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Analysis of experiment Peer reviewed |
|---|---|
| Interventions | 5-hydroxytryptophan (5-HTP) lysergic acid diethylamide (LSD) |
| Topics | LSD |
| Keywords | Clinical psychology Personality Rorschach test Psychosis |
| Citations | 10 |
| Key findings | The analysis raises issues about the measurement and validity of using psychological tests to assess LSD-induced psychosis. |
Abstract
The present analysis pertains to the experiment reported by Brengelmann, Pare and Sandler (15) to assess the effect of 5-hydroxytryptophan (5-HTP) on lysergic acid diethylamide (LSD) by means of psychological tests. In the following, problems of measurement and validity of the LSD- “psychosis” are discussed.
Comparable studies
Other experimental studies on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Neural correlates of the LSD experience revealed by multimodal neuroimaging. Human participants | 2016 | Experimental study | |
| Crystal structure of an LSD-bound human serotonin receptor | 2017 | Experimental study with structural biology and molecular dynamics simulations | |
| Lysergic Acid Diethylamide: Sensitive Neuronal Units in the Midbrain Raphe Midbrain neurons containing serotonin | 1968 | Experimental study | |
| Connectome-harmonic decomposition of human brain activity reveals dynamical repertoire re-organization under LSD. Human brain | 2017 | Experimental study | |
| LSD-Assisted Psychotherapy in Patients with Terminal Cancer Cancer patients | 1973 | Experimental study | n = 60 |
Citations in the library
Cited by 5
- Serotonergic psychedelics and personality: A systematic review of contemporary research Neuroscience & Biobehavioral Reviews February 13, 2018
- Alleviation of the Psychological Effects of LSD in Man by 5-Hydroxytryptophan Journal of Mental Science October 1, 1958
- Cognitive functioning associated with acute and subacute effects of classic psychedelics and MDMA - a systematic review and meta-analysis. Scientific Reports June 26, 2024
- Using Psychedelics in Clinical Practice: Comparing Therapeutic Uses and Potential Harms. Current reviews in clinical and experimental pharmacology 2023
- Efeitos agudos e subagudos de dose única de Ayahuasca no reconhecimento de expressões faciais May 4, 2020
Cites 3
- Lysergic Acid Diethylamide (LSD-25): VI. Effect upon Recall and Recognition of Various Stimuli The Journal of Psychology April 1, 1955
- Comparative subjective effects of seven drugs including lysergic acid diethylamide (LSD-25). Journal of Abnormal & Social Psychology November 1, 1955
- Alleviation of the Psychological Effects of LSD in Man by 5-Hydroxytryptophan Journal of Mental Science October 1, 1958