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Severe Solar Maculopathy Associated with the use of Lysergic Acid Diethylamide (LSD)

Dwain Fuller

American Journal of Ophthalmology April 1, 1976 DOI: 10.1016/0002-9394(76)90295-6 (opens in new tab) via OpenAlex

Summary

AI-generated from the abstract

A 23-year-old man suffered severe damage to the macula, the central part of the retina, after staring at the sun while under the influence of a hallucinogenic drug. Repeated imaging of the back of the eye, including fundus photography and fluorescein angiography, showed clear injury concentrated in the retinal pigment epithelium, a key layer that supports the retina's light-sensing cells.

Study at a glance

Characteristics Case study Case report Peer reviewed
Sample size 1
Population 23-year-old man
Topics LSD
Keywords Maculopathy Retinal pigment epithelium Fundus photography Fluorescein angiography Medicine
Citations 52
Key finding Sun gazing during a hallucinogenic drug-induced state caused severe macular damage with prominent focal injury to the retinal pigment epithelium.

Abstract

A 23-year-old man sustained severe macular damage by sun gazing during a hallucinogenic drug-induced state. Sequential fundus photography and fluorescein angiography documented prominent focal injury to the retinal pigment epithelium.

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