Effects of Lysergic Acid Diethylamide (LSD) on the Time Sense of Normals
A M A Archives of Neurology & Psychiatry September 1, 1957 DOI: 10.1001/archneurpsyc.1957.02330390103013 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Normal subjects |
| Intervention | Lysergic acid diethylamide (LSD) |
| Dose | moderate to low doses |
| Topics | LSD |
| Keywords | Schizophrenia object-oriented programming Time perception Audiology Sense electronics Population Stereochemistry |
| Citations | 21 |
| Key findings | Moderate to low doses of LSD produce alterations in time perception in normal subjects, specifically overestimation of short audible durations, in the direction characteristic of schizophrenia. |
Abstract
Introduction Much of the interest in lysergic acid diethylamide (LSD) is due to its capacity to produce schizophrenic-like behavior when administered in extremely small quantities. 4,6 Among the reported changes resulting from LSD have been alterations in time perception. DeShon, Rinkel, and Solomon, 1 found changes in the form of experiences of acceleration, retardation, or nonexistence of time, while true disorientation was not observed. The subjects of Hoch, Cattell, and Pennes 3 reported the passage of time as slowed, an experience not uncommon to schizophrenic patients. An objective study of the time sense of schizophrenics 5 indicated that this population overestimates short audible durations to a significantly greater degree than do normal controls. The purpose of the present investigation was to determine whether moderate to low doses of LSD produce alterations in the time sense of normal subjects in the direction characteristic of schizophrenia, using the same method as reported