Severe Neurological Sequelae after a Recreational Dose of LSD
Rachel Aakerøy, Wenche Rødseth Brede, Stian Bergseng Stølen, Hege‐merete Krabseth, Lisbeth Solem Michelsen, Trine Naalsund Andreassen, Tiina Ader, Joachim Frost, Grete Slettom, Ole Martin Steihaug, Lars Slørdal
Journal of Analytical Toxicology October 2, 2020 DOI: 10.1093/jat/bkaa145 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A young man with unremarkable medical history |
| Topics | LSD |
| Keywords | Cardiorespiratory fitness Adverse effect Recreational use Serum concentration Cardiorespiratory arrest Physiology Pharmacology Anesthesia |
| Citations | 9 |
| Key findings | LSD may cause seizure, cardiorespiratory arrest, and severe neurological sequelae in previously healthy individuals. |
Abstract
Abstract A young man with an unremarkable medical history suffered a seizure with subsequent cardiorespiratory arrest and severe neurological sequelae after ingesting a blotter. Analysis of a similar blotter and a serum sample obtained 3 h after the event detected lysergic acid diethylamide (LSD) at an amount of 300 µg in the blotter and at a concentration of 4.0 ng/mL (12.4 nmol/L) in the serum. No other drugs were present in concentrations which may confer significant effects. In addition, no individual traits which would make the patient particularly susceptible to adverse LSD effects have subsequently been identified. This suggests that LSD may confer toxic effects in previously healthy individuals.