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Carotid Artery Occlusion Following Ingestion of LSD

Abraham Lieberman, William Bloom, Pulla S. Kishore, Joseph P. Lin

Stroke March 1, 1974 DOI: 10.1161/01.str.5.2.213 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population 20-year-old white woman
Intervention LSD
Topics LSD
Keywords Ingestion Vasoconstriction Occlusion Angiography Cardiology Anesthesia Internal carotid artery Carotid arteries Vasodilation
Citations 37
Key findings LSD ingestion was associated with marked constriction of the internal carotid artery that progressed to occlusion, leading to hemiplegia.

Abstract

A 20-year-old white woman developed a left hemiplegia following the ingestion of LSD. Initial angiography revealed marked constriction of the internal carotid artery at the level of the siphon which, in a few days, was converted to occlusion of the carotid artery at that level. It is suggested that LSD, an amine derivative of the ergot alkaloids, was responsible for the initial vasoconstriction and subsequent occlusion.