A Chronic Impairment of Colour Vision in Users of LSD
The British Journal of Psychiatry May 1, 1982 DOI: 10.1192/bjp.140.5.518 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 77 |
| Population | Users of LSD and controls |
| Duration | Average two years after last exposure |
| Topics | LSD |
| Keywords | Optometry Visual impairment Computer vision Artificial intelligence |
| Citations | 40 |
| Key findings | LSD users performed worse on a color discrimination test than controls, and users without flashbacks performed better than users with flashbacks. |
Abstract
Summary Forty-six users of the hallucinogen lysergic acid diethylamide were compared with 31 controls on a test of colour discrimination an average of two years after their last exposure to the drug. Controls performed better than users, and LSD users without flashbacks performed better than users with flashbacks. An analysis of variance between the three groups was significant at P <0.001. This study suggests that some users of LSD may have a sustained or irreversible impairment in colour discrimination.
Comparable studies
Other observational and cohort studies on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Increased Global Functional Connectivity Correlates with LSD-Induced Ego Dissolution. Human participants | 2016 | Observational cohort | |
| Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD and psilocybin Humans | 2017 | Observational study | |
| Classic psychedelic use is associated with reduced psychological distress and suicidality in the United States adult population. USA adult respondents from the National Survey on Drug Use and Health (2008-2012) | 2015 | Observational cohort | n = 190,000 |
| Psychedelics not linked to mental health problems or suicidal behavior: A population study Randomly selected United States adults | 2015 | Observational cohort | n = 135,095 |
| Whole-Brain Multimodal Neuroimaging Model Using Serotonin Receptor Maps Explains Non-linear Functional Effects of LSD. Healthy human participants | 2018 | Observational study with computational modeling |
Citations in the library
Cited by 20
- Acute, subacute and long-term subjective effects of psilocybin in healthy humans: a pooled analysis of experimental studies Journal of Psychopharmacology September 20, 2010
- Visual Phenomenology of the LSD Flashback Archives of General Psychiatry August 1, 1983
- The psychopharmacology of hallucinogens. Neuropsychopharmacology April 1, 1996
- Adverse consequences of lysergic acid diethylamide Addiction October 1, 1993
- d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology International Journal of Molecular Sciences November 23, 2016
and 15 more in the library
Cites 4
- Lysergic Acid Diethylamide: Sensitive Neuronal Units in the Midbrain Raphe Science August 16, 1968
- Flashbacks: Recurrent Intrusive Images After the Use of LSD American Journal of Psychiatry October 1, 1969
- LSD Revisited Archives of General Psychiatry 1971
- Effects of LSD-25 on brain serotonin. Journal of Pharmacology and Experimental Therapeutics November 1, 1961