The dangers of LSD. Analysis of seven months' experience in a university hospital's psychiatric service
JAMA August 8, 1966 DOI: 10.1001/jama.197.6.389 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case series Case report Peer reviewed |
|---|---|
| Sample size | 70 |
| Population | Patients with adverse reactions to LSD taken outside medical or research settings |
| Topics | LSD |
| Keywords | Ingestion |
| Citations | 61 |
| Key findings | Widespread non-medical use of LSD is a cause for concern due to the varied and severe psychiatric side effects observed. |
Abstract
The symptoms, diagnostic categories, and general characteristics of patients in 70 cases of adverse reactions to lysergic acid diethylamide tartrate (LSD) are varied. Psychiatric side effects ranged from depressive reaction to psychotic states. In all cases, LSD ingestion occurred separately and apart from medical-experimental and psychiatric-therapeutic models of LSD usage. Findings based on these cases and from observations made on LSD users in the community indicate that widespread use of LSD is a cause for concern.
Comparable studies
Other case reports and case series on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users Persons who ingested large doses of MDMA | 1991 | Case study | n = 2 |
| Further Studies in the Therapeutic Value of Lysergic Acid Diethylamide in Mental Illness Patients with mental illness | 1957 | Case series | |
| Coma, Hyperthermia, and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases People who self-administered large amounts of pure LSD powder intranasally | 1975 | Case series | n = 8 |
| Using a MDMA- and LSD-Group Therapy Model in Clinical Practice in Switzerland and Highlighting the Treatment of Trauma-Related Disorders Patients with chronic complex post-traumatic stress disorder (c-PTSD), dissociative,... | 2022 | Case series | |
| Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD) Patients who developed persistent palinopsia after LSD ingestion | 1996 | Case series | n = 3 |
Citations in the library
Cited by 14
- The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms Journal of Psychopharmacology November 18, 2016
- The psychopharmacology of hallucinogens. Neuropsychopharmacology April 1, 1996
- On the Use and Abuse of LSD Archives of General Psychiatry March 1, 1968
- Adverse consequences of lysergic acid diethylamide Addiction October 1, 1993
- Treatment of alcoholism using psychedelic drugs: a review of the program of research. Journal of Psychoactive Drugs 1998
and 9 more in the library
Cites 4
- Complications Associated with Lysergic Acid Diethylamide (LSD-25) JAMA July 14, 1962
- Mescaline, LSD, Psilocybin, and Personality Change a Review† Psychiatry May 1, 1963
- "MODEL PSYCHOSIS" PRODUCED BY INHALATION OF GASOLINE FUMES American Journal of Psychiatry February 1, 1964
- Comparison of the LSD-25 Experience and Delirium Tremens Archives of General Psychiatry July 1, 1959