Untoward Reactions to Lysergic Acid Diethylamide (LSD) Resulting in Hospitalization
William A. Frosch, Edwin Robbins, Marvin Stern
New England Journal of Medicine December 2, 1965 DOI: 10.1056/nejm196512022732302 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Historical analysis Peer reviewed |
|---|---|
| Topics | LSD |
| Keywords | Ingestion Etiology Hallucinogen |
| Citations | 115 |
| Key points | Argues that pharmacologic agents capable of producing changes in psychic state, such as LSD, represent exceptions to the typical pattern of medical research, often creating new clinical syndromes as unintended by-products of abuse or physician error. |
Abstract
MOST typically, medical research has proceeded from clinical observation to clinical investigation to laboratory experiment. Some of the striking exceptions to this pattern have been studies of a variety of pharmacologic agents that are capable of producing changes in psychic state. These drugs, first isolated or synthesized in the laboratory, occasionally create a new clinical syndrome or a new etiology of an old syndrome as an undesirable by-product of individual abuse or poor judgment by the physician.A sudden surge of admissions to the Bellevue Psychiatric Division after ingestion of d-lysergic acid diethylamide (LSD) prompted us to review the history . . .
Comparable studies
Other theoretical and historical papers on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The Experimental Use of Psychedelic (LSD) Psychotherapy | 1970 | Historical analysis | |
| LSD: My Problem Child | 1981 | Historical analysis | |
| On the Use and Abuse of LSD | 1968 | Theoretical or philosophical paper | |
| The Use of Music in Psychedelic (LSD) Psychotherapy | 1972 | Theoretical or philosophical paper | |
| Flashbacks: Recurrent Intrusive Images After the Use of LSD | 1969 | Theoretical or philosophical paper |
Citations in the library
Cited by 34
- The psychopharmacology of hallucinogens. Neuropsychopharmacology April 1, 1996
- In Vivo and in Vitro Chromosomal Damage Induced by LSD-25 New England Journal of Medicine November 16, 1967
- On the Use and Abuse of LSD Archives of General Psychiatry March 1, 1968
- Adverse Events in Studies of Classic Psychedelics JAMA Psychiatry September 4, 2024
- Treatment of alcoholism using psychedelic drugs: a review of the program of research. Journal of Psychoactive Drugs 1998
and 29 more in the library