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Marcelo Febo

5 papers in the library · 29 citations · publishing 2015-2025

Papers

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Effects of cannabis smoke and oral Δ9THC on cognition in young adult and aged rats

Psychopharmacology February 7, 2025 Sabrina Zequeira, Emely A. Gazarov, Alara A. Güvenli et al.

With increasing legalization of recreational and medical cannabis, use of this drug is growing rapidly among older adults. As cannabis can impair cognition in young adults, it is critically important to understand how its consumption interacts with the cognitive profile of aged subjects, who are already at increased risk of decline. The current study was designed to determine how cannabis...

Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects

bioRxiv (Cold Spring Harbor Laboratory) September 29, 2024 Sabrina Zequeira, Emely A. Gazarov, Alara A. Güvenli et al. preprint

With increased legalization of recreational and medical cannabis, use of this drug is growing rapidly among older adults. As cannabis use can impair cognition in young adults, it is critically important to understand how consumption interacts with the cognitive profile of aged individuals, who are already at increased risk of decline. The current study was designed to determine how cannabis...

Effects of inhaled cannabis high in Δ9-THC or CBD on the aging brain: A translational MRI and behavioral study

Frontiers in Aging Neuroscience February 1, 2023 Aymen H. Sadaka, Justin Canuel, Marcelo Febo et al. 29 citations

With the recent legalization of inhaled cannabis for medicinal and recreational use, the elderly represents one of the newest, rapidly growing cohorts of cannabis users. To understand the neurobiological effects of cannabis on the aging brain, 19-20 months old mice were divided into three groups exposed to vaporized cannabis containing ~10% Δ9-THC, ~10% CBD, or placebo for 30 min each day....

KB220Z™ a Pro-Dopamine Regulator Associated with the Protracted, Alleviation of Terrifying Lucid Dreams. Can We Infer Neuroplasticity-induced Changes in the Reward Circuit?

Journal of reward deficiency syndrome and addiction science 2016 Thomas Mclaughlin, Marcelo Febo, Rajendra D Badgaiyan et al.

Recent reports by our laboratory have indicated that lucid dreams may be linked to psychiatric conditions, including Attention Deficit Hyperactivity Disorder (ADHD) and other Reward Deficiency Syndrome-related diagnoses. In the latter case, it has been our observation that such lucid dreams can be unpleasant and frequently terrifying. We present four cases of a dramatic and persistent...

Putative dopamine agonist (KB220Z) attenuates lucid nightmares in PTSD patients: role of enhanced brain reward functional connectivity and homeostasis redeeming joy.

Journal of Behavioral Addictions June 1, 2015 Thomas Mclaughlin, Kenneth Blum, Marlene Oscar-Berman et al.

Background: Lucid dreams are frequently pleasant and training techniques have been developed to teach dreamers to induce them. In addition, the induction of lucid dreams has also been used as a way to ameliorate nightmares. On the other hand, lucid dreams may be associated with psychiatric conditions, including Post-Traumatic Stress Disorder (PTSD) and Reward Deficiency Syndrome-associated...

DOI: 10.1556/2006.4.2015.008 (opens in new tab) Full text (opens in new tab) Humans Catecholamines Neprilysin Monoamine oxidase +15