Modulating the default mode network with deep TMS: a proof-of-concept framework with potential relevance to circuits implicated in lack of awareness of cognitive decline.

A proof-of-concept framework proposes that deep transcranial magnetic stimulation (deep TMS) can modulate the default mode network, a brain circuit linked to self-referential thought. This modulation may have relevance for addressing lack of awareness of cognitive decline, a symptom common in neurodegenerative conditions. The framework suggests deep TMS could be used to alter activity in this network, potentially improving insight into one's own cognitive status. The authors present this as a conceptual foundation for future research rather than a completed study.

Study at a glance

Abstract

Modulating the default mode network with deep TMS: a proof-of-concept framework with potential relevance to circuits implicated in lack of awareness of cognitive decline.