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Effect of esketamine and etomidate anesthesia on neuroplasticity in electroconvulsive therapy for treatment-resistant depression.

World J Psychiatry September 19, 2025 DOI: 10.5498/wjp.v15.i9.109458 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Population Patients with treatment-resistant depression undergoing electroconvulsive therapy
Interventions Esketamine Etomidate
Topics Depression Esketamine Neuroplasticity
Key findings Esketamine anesthesia increased neuroplasticity markers (e.g., BDNF) compared to etomidate during ECT for treatment-resistant depression.

Abstract

Effect of esketamine and etomidate anesthesia on neuroplasticity in electroconvulsive therapy for treatment-resistant depression.