Scientific Reports - The Consciousness Library

The role of cognitive flexibility and psychological well-being in the effect of mindfulness on problematic internet use

Scientific Reports August 26, 2025 Gülin Yazıcı Çelebi, Sunay Güngör, Feridun Kaya

With the widespread use of digital technologies today, the Internet has become an indispensable part of life but has also led to negative outcomes such as problematic internet use in some individuals. Problematic internet use is seen as a critical risk factor that negatively impacts individuals’ academic, social, and psychological functioning. Research has presented a lot of evidence in recent...

DOI: 10.1038/s41598-025-16858-w Full text

Ketamine and olanzapine alter behaviour and prefrontal-cortex BDNF differentially in male and female rats

Scientific Reports August 23, 2025 Kalin Manooki, Mahdieh Gholami, Maryam Eslami et al. 3 citations

Schizophrenia is a severe chronic neuropsychiatric disorder with a wide-range of cognitive and mental deficits and different categories of symptoms including positive, negative, and cognitive symptoms. In rodents, sub-chronic ketamine administration is a common method to induce a schizophrenia-like state. Olanzapine, an atypical antipsychotic medication, is used for the treatment and management...

DOI: 10.1038/s41598-025-15499-3 Full text Ketamine Olanzapine Prefrontal cortex Schizophrenia object-oriented programming +3

Effects of brief mindfulness meditation on compassion and personal distress using the socio-affective video task.

Scientific Reports August 22, 2025 Gabriela Górska, Paweł Holas

Recent findings indicate that meditation may enhance compassion and foster prosocial actions aimed at helping others. In the present preregistered research, we aimed to test hypotheses regarding the positive impact of a single short, guided mindfulness meditation on compassionate and personal distress responses, measured with the Socio-affective Video Task (SoVT), and the possible mechanisms of...

DOI: 10.1038/s41598-025-16416-4 Full text

CATT haplotype of the FKBP5 gene and dissociative phenomenology

Scientific Reports August 5, 2025 S. Moser, Hans Knoblauch, B. Müller-Myhsok et al.

Survival mechanisms are evolutionary grown behaviors in life-threatening situations. They are thought to be determined by genetic patterns involved in stress systems, such as the control of the hypothalamic-pituitary-adrenal (HPA) axis. FK506 binding protein 5 (FKBP5) is a co-chaperone that is involved in modulating glucocorticoid receptor (GR) sensitivity in response to stress. Dissociation is...

DOI: 10.1038/s41598-025-13865-9 Full text

Mindfulness and academic performance among nursing students in Saudi Arabia: a cross-sectional study.

Scientific Reports July 28, 2025 Darin Mansor Mathkor 3 citations

Mindfulness has recently gained attention in academia for its potential to improve cognitive performance, collaboration and mental well-being. This study aimed to assess mindfulness levels among Saudi nursing graduate students and examine their association with grade point average (GPA) scores in academic examinations. This cross-sectional study used the Five Facet Mindfulness Questionnaire...

DOI: 10.1038/s41598-025-11911-0 Full text Mindfulness Attentional capacity Cognitive skills Nursing students

Metabolomic profiles impacted by brief mindfulness intervention with contributions to improved health.

Scientific Reports July 25, 2025 Yi-Yuan Tang, Jeffrey S Patterson, Rongxiang Tang et al. 3 citations

Mounting evidence indicates that mindfulness-based interventions improve physical and mental health. However, whether brief mindfulness intervention supports health benefits by regulating metabolic profiles is poorly understood. To address this gap, this randomized controlled trial compared ten 1-hour sessions of integrative body-mind training (IBMT) with relaxation training (RT) in 42...

DOI: 10.1038/s41598-025-12067-7 Full text Amino acid metabolism Integrative body-mind training Lipid metabolism Metabolomics +1

Quantitative and qualitative influences of spiritual connection and natural imagery on perception of art in clinical psychedelic dosing settings.

Scientific Reports July 21, 2025 Suhjung Janet Lee, Claudia Epland, Noah Kaitz et al. 1 citation

Psychedelic clinical study environments are frequently visually manipulated, such as art; however, there has been little study of how the art selected for display impacts individual responses to the overall setting. To examine how individual self-identities shape perceptions of art used in a clinical psychedelic dosing environment, this study used a community-engaged mixed-methods approach....

DOI: 10.1038/s41598-025-12613-3 Full text Nature Psychedelic Set and setting Spirituality

Rumination and alexithymia serially mediate the relationship between mindfulness and anxiety symptoms in Chinese university students.

Scientific Reports July 16, 2025 Junchao Yuan, Luyu Chen, Hongye Geng 1 citation

Anxiety symptoms are highly prevalent among Chinese university students, significantly impairing psychosocial functioning. Although mindfulness has been identified as a protective psychological factor, the precise mechanisms underlying its association with anxiety symptom alleviation remain insufficiently understood. This study investigates the serial mediation effects of rumination and...

DOI: 10.1038/s41598-025-11973-0 Full text Mindfulness Alexithymia Anxiety symptoms Mediation analysis +2

Effectiveness of an online mindfulness based stress reduction intervention on psychological distress among patients with COVID19 after hospital discharge.

Scientific Reports July 13, 2025 Maryam Mozaffari, Manijeh Naderi, Hosein Zahednezhad et al. 1 citation

Given the high prevalence of psychological complications during pandemics such as COVID-19, it is imperative to identify effective psychological interventions that can improve the mental health of patients and community members. The effectiveness of mindfulness-based intervention in discharged patients with infectious respiratory diseases, particularly during pandemics, has been examined in a...

DOI: 10.1038/s41598-025-11289-z Full text Anxiety Depression Psychological distress Covid-19 survivors +2

Mind wandering during creative incubation predicts increases in creative performance in a writing task.

Scientific Reports July 9, 2025 Colin McDaniel, Assal Habibi, Jonas Kaplan 2 citations

Previous studies suggest that taking breaks from creative problem solving (i.e., incubation periods) enhances subsequent performance, possibly due to mind wandering during these breaks. The present preregistered study investigated whether different types of incubation periods, designed to either promote or suppress mind wandering, influence creativity in a writing task. Participants wrote two...

DOI: 10.1038/s41598-025-09736-y Full text Mind wandering Problem solving Creative writing performance Enhancing creativity +3

Pupil constrictions to subjective brightness as a gateway to probe consciousness in non communicating patients.

Scientific Reports July 9, 2025 Aude Sangare, Cécile Eymond, Lise Jodaitis et al. 1 citation

Retinal illumination primarily determines pupil size, yet extra-retinal factors like subjective brightness also influence pupillary responses. Previous works reported that in healthy individuals, stimuli whose semantic content evokes brightness cause greater pupillary constriction than control stimuli of similar luminance. This study adapted this approach and tested a passive task to assess...

DOI: 10.1038/s41598-025-06941-7 Full text Consciousness assessment awareness Inner awareness Residual cognition Signs of consciousness +14

In silico investigation of ketamine and methylphenidate drug-drug conjugate for MDD and ADHD treatment using MD simulations and MMGBSA

Scientific Reports July 8, 2025 Beenish Asrar, Nouman Ali, Imran Ali et al.

Major depressive disorder (MDD) and Attention-deficit hyperactivity disorder (ADHD) are pervasive psychiatric disorders characterized by impaired memory, sustained attention/motivation, and depression. FDA-approved Ketamine is an antidepressant drug but it affects cognitive abilities. Methylphenidate is the drug used for the treatment of ADHD. Chronic treatment overcomes attention and mental...

DOI: 10.1038/s41598-024-82302-0

An experimental study focusing on mindfulness to capture how our contacts with dogs can promote human well-being

Scientific Reports July 2, 2025 Catherine E. Amiot, Mylène Quervel-Chaumette, Christophe Gagné et al. 7 citations

Pet ownership per se has not been reliably associated with increased human well-being and health. Furthermore, the specific psychological mechanisms and behavioral dynamics through which the presence of pets could yield higher human wellness remain under-investigated. Conducted among dog owners and their dogs, the current experiment investigates if a specific psychological factor - i.e.,...

DOI: 10.1038/s41598-025-00872-z Full text

Mindfulness-based stress reduction intervention during pregnancy changes maternal brain.

Scientific Reports July 1, 2025 Yvan Gomez, Ayako Nakaki, Allegra Conti et al. 3 citations

Our aim is to evaluate the effect of a structured stress reduction intervention based on mindfulness during pregnancy on the maternal brain. We report a secondary analysis of IMPACT BCN, a randomized clinical trial including pregnant women randomly allocated to 8-week Mindfulness-Based Stress Reduction (n = 41) or usual care (without any intervention, n = 35). Maternal magnetic resonance (MR)...

DOI: 10.1038/s41598-025-07787-9 Full text MRI Mindfulness-based stress reduction Pregnancy Small-for-gestational age +8

The relationship between mindfulness, psychological flexibility, and symptom severity in persons with schizophrenia-spectrum-disorders: a cross-sectional study.

Scientific Reports June 4, 2025 Inge Hahne, Julia Segerer, Marco Zierhut et al. 3 citations

The effectiveness of mindfulness-based interventions (MBIs) in enhancing mental well-being and reducing positive, negative, and depressive symptoms in schizophrenia spectrum disorders (SSD) has been increasingly supported by evidence. However, the underlying mechanisms of MBIs require further examination. Psychological flexibility (PF), typically assessed through cognitive fusion, has been...

DOI: 10.1038/s41598-025-03380-2 Full text Mindfulness Depressive symptoms Mediation Negative symptoms +3

Population-based estimates of different dosage types of psychedelic use across socio-demographic groups in Germany.

Scientific Reports May 29, 2025 Sebastian Sattler, Suzanne Wood, Margit Anne Petersen et al.

Psychedelic drugs, particularly taking small amounts of psychedelics in a cyclical pattern over days (so-called microdosing), have garnered growing scientific and public interest, but representative data on different dosage levels is scarce. To better understand this trend, we surveyed a nationwide sample of 11,299 adults in Germany. The survey assessed lifetime and past six-month psychedelic...

DOI: 10.1038/s41598-025-03873-0 Full text Psychedelics Drug use Germany Demographics +1

The effect of a synthetic cannabinoid agonist (nabilone) on unimodal tactile illusion correlates with a psychometric scores in healthy volunteers

Scientific Reports May 27, 2025 Faiz Mohammed Kassim, Alexander J. W. Davey, Sophie Tod et al.

Our previous studies showed that dexamphetamine, an indirect dopamine agonist, widens Stimulus Binding Windows (BWs) in healthy subjects. The present study aimed to investigate the effect of nabilone, a synthetic cannabinoid agonist, on the BWs in a unimodal illusion: the tactile funneling illusion (TFI). The study also aimed to study the association between tactile illusion with psychometric...

DOI: 10.1038/s41598-025-02280-9 Full text Cannabinoid Illusion Audiology Agonist +3

Psilocybin mitigates behavioral despair and cognitive impairment in treatment-resistant depression model using wistar kyoto rats.

Scientific Reports May 26, 2025 Zitong Wang, Brett Robbins, Ryan Zhuang et al. 4 citations

Major depressive disorder (MDD) is a leading cause of disability that affects over 300 million people globally. Despite multiple antidepressant trials, approximately one-third of MDD patients remain symptomatic, progressing to treatment-resistant depression (TRD). This persistence possibly is due to the multifaceted etiology of TRD, encompassing biological, psychological, and environmental...

DOI: 10.1038/s41598-025-03383-z Full text Neuroscience research Depression treatment Psychedelics Mental health therapy +1

Similarities and differences between natural sleep and urethane anesthesia.

Scientific Reports May 25, 2025 Jurij Brankačk, Yevgenij Yanovsky, Adriano B. L. Tort et al. 6 citations

Slow oscillations dominate the EEG or local field potential (LFP) of mammals during specific periods within natural sleep and anesthesia. Such similarities have led to the use of anesthesia as a model to study sleep and state-dependent changes of consciousness. Previous research has documented the similarities between the activated state of urethane anesthesia and natural REM sleep,...

DOI: 10.1038/s41598-025-01762-0 Full text Parietal cortex Slow oscillation Urethane anesthesia Δ waves +4

Examining cognitive differences in expert meditators and non-meditators older adults.

Scientific Reports May 15, 2025 Florence Requier, Hamed Mohammadi, Harriet Demnitz-King et al.

With aging, slight changes in some cognitive processes can be observed. Therefore, we aimed to assess if meditation expertise is associated with preserved cognition in key domains affected in aging. We used data from two older-adult samples of the Medit-Ageing Age-well Study: 135 non-meditators and 27 expert meditators. We examined group differences in four objective cognitive domains...

DOI: 10.1038/s41598-025-00226-9 Full text Attention Executive function Expert meditators Older age +9

A quasiexperimental study of assessing the impact of stress management program on health science students at Kuwait University.

Scientific Reports May 12, 2025 Naser M Alotaibi, Latifah Alenezi, Feddah M Ahmad et al. 1 citation

The purpose of this research was to study the effectiveness of a stress management program among students at the Health Science Center (HSC), Kuwait University. This study utilized a quasiexperimental research design in which the participants were randomly assigned to one of two groups: (1) the control group or (2) the experimental (intervention) group. The participants received a comprehensive...

DOI: 10.1038/s41598-025-01633-8 Full text Anxiety Depression Meditation Cognitive behavioral therapy +3

A comparative study of the impact of meditation and Buddhist five precepts on stress and depression between older adults and younger adults.

Scientific Reports May 6, 2025 Nahathai Wongpakaran, Sirilux Klaychaiya, Chompimaksorn Panuspanudechdamrong et al. 2 citations

Older adults frequently face a myriad of physical and mental health challenges, which can contribute to feelings of stress and subsequent depression. Nevertheless, with age often comes a wealth of life experience and resilience. Perceived stress commonly predicts depression across all age groups, while meditation has been associated with lower levels of depression. Additionally, adherence to...

DOI: 10.1038/s41598-025-99430-w Full text Buddhism Meditation Mindfulness Five precepts +16

Relationship and personality factors predict longitudinal changes in dream content

Scientific Reports May 3, 2025 John Balch, Rachel Raider, Chanel Reed et al. 1 citation

Researchers have established that dreams are intensely social and populated by diverse characters, including important figures from the dreamer's daily life. This study examines the types of characters that appeared in participant dreams over two weeks. We found that the majority of dreams include strangers in addition to known individuals, and that personality measures impact the likelihood of...

DOI: 10.1038/s41598-025-99018-4 Full text Dream Personality Content measure theory

Childhood experiences and adult prayer or meditation in 22 countries around the world

Scientific Reports April 30, 2025 Matt Bradshaw, Victor Counted, Tim Lomas et al.

Few studies have examined how childhood experiences and characteristics shape daily prayer or meditation in adulthood across countries around the world using nationally-representative data. The current study addresses this limitation by analyzing data from the Global Flourishing Study (GFS), an international survey of 202,898 individuals from 22 geographically, economically, and culturally...

DOI: 10.1038/s41598-025-99796-x Full text

Mindfulness training decreases the habituation response to persistent food stimulation.

Scientific Reports April 25, 2025 Alyssa Torske, Doris Schicker, Jessica Freiherr et al. 3 citations

Modern societies and their obesogenic environments expose individuals to persistent food stimulation. This frequent exposure can cause sensory systems to habituate or desensitize to food-related sensory stimulation. This can, in turn, lead to the reduction of pleasure associated with eating, which can elicit overeating behavior to attain the desired pleasurable effect. However, frequently...

DOI: 10.1038/s41598-025-90172-3 Full text Mindfulness Eating behavior Habituation response Neuroimaging +1

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