Kalin Manooki

Ketamine and olanzapine alter behaviour and prefrontal-cortex BDNF differentially in male and female rats

Scientific Reports August 23, 2025 Kalin Manooki, Mahdieh Gholami, Maryam Eslami et al. 3 citations

Schizophrenia is a severe chronic neuropsychiatric disorder with a wide-range of cognitive and mental deficits and different categories of symptoms including positive, negative, and cognitive symptoms. In rodents, sub-chronic ketamine administration is a common method to induce a schizophrenia-like state. Olanzapine, an atypical antipsychotic medication, is used for the treatment and management...