Helvetica Chimica Acta
September 1, 2009
Kuan‐Hon Lim, Toh‐Seok Kam
14 citations
Abstract Conomicidines A and B (1a and 2a, resp.) together with the diastereomeric isoconomicidines A and B (1b and 2b, resp.) were isolated from Tabernaemontana corymbosa as unresolvable mixtures of the (1′S,2′S)‐ and (1′R,2′R)‐diastereoisomers (i.e., 1a and 1b; 2a and 2b). These novel natural products are constituted from the union of an iboga alkaloid, ibogaine, and hydroxycinnamyl alcohol...
Helvetica Chimica Acta
November 3, 1976
Ernest Wenkert, David W. Cochran, Hugo Emilio Gottlieb et al.
48 citations
Abstract The carbon shifts of the Iboga‐type alkaloids catharanthine, voacangine, coronaridine, ibogaine, dihydrocatharanthine and epiibogamine were recorded and correlated with the conformation of the natural bases. A 13C‐NMR. analysis of heyneanine determined its C(19) configuration and a similar study of epiheyneanine proved its structure.
Helvetica Chimica Acta
June 1, 1965
Abstract: Aus frischen Fruchtkörpern von Amanita muscaria (L. ex FR.) HOOKER, wurden Prämuscimol, C5H8O5N2, Smp. 145° (Zers.) und Muscazon, C5H6O4N2, isoliert. Beide Substanzen reagieren mit Ninhydrin gelb. Prämuscimol geht leicht unter Wasser‐ und CO2‐Abspaltung in Muscimol über. Prämuscimol wirkt wie Muscimol stark narkosepotenzierend.
Helvetica Chimica Acta
1965
G. F. R. Müller, C. H. Eugster
AbstractEs wird die Isolierung einer Substanz mit stark narkosepotenzierender Wirkung, des Muscimols C4H6O2N2, Smp. 155–156°, aus dem Fliegenpilz (Amanita muscaria (L. ex FR.) HOOKER) beschrieben. Die Substanz hat salzartigen Charakter (Betain). Muscimol ist kein genuiner Inhaltsstoff des Fliegenpilzes, sondern entsteht bei der Aufarbeitung aus einer labilen Vorstufe, die ähnliche...
Helvetica Chimica Acta
1964
A. Brossi, F. Schenker, W. Leimgruber
32 citations
Abstract The four known Cactus alkaloids anhalamine (II), anhalidine (III), rac . anhalonidine (IV) and rac pellotine (V) have been synthesized starting from mescaline (I) by new and simple procedures.
Helvetica Chimica Acta
1959
A. Hofmann, Richard R. Heim, André Brack et al.
225 citations
Abstract The psychotropically active principles of the Mexican hallucinogenic fungus Psilocybe maxicana H EIM have been isolated and obtained in crystalline form. The two new substances, which have been called psilocybin and psilocin , are present in the fruit bodies, the artificially cultivated mycelium and in the sclerotia. The dried mushroom contains 0.2 to 0.4 per cent psilocybin. Psilocin...
Helvetica Chimica Acta
1959
F. Troxler, Frauke Seemann, A. Hofmann
69 citations
Abstract Various modifications were made in the molecular structure of the natural psychotropic substances psilocybin (I) and psilocin (11) to obtain an insight into the relationship between structure and psychotropic action of this group of substances. A description is given of the synthesis and properties of the position isomers of I and II with a phosphoryloxy or hydroxy group in position 5,...