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13C‐NMR. Spectroscopy of Naturally Occurring Substances. XLV. Iboga Alkaloids

Ernest Wenkert, David W. Cochran, Hugo Emilio Gottlieb, Edward W. Hagaman, Raimundo Braz‐Filho, F. J. A. Matos, Maria Iracema L. Machado

Helvetica Chimica Acta November 3, 1976 DOI: 10.1002/hlca.19760590719 (opens in new tab)

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AI-extracted from the abstract
Characteristics Peer reviewed
Measures 13C-NMR
Topics Ibogaine
Citations 48
Key points Reports 13C-NMR carbon shifts for six Iboga-type alkaloids and correlates them with the conformation of the natural bases. The authors state that 13C-NMR analysis established the C(19) configuration of heyneanine and, in a similar study, proved the structure of epiheyneanine.

Abstract

Abstract The carbon shifts of the Iboga‐type alkaloids catharanthine, voacangine, coronaridine, ibogaine, dihydrocatharanthine and epiibogamine were recorded and correlated with the conformation of the natural bases. A 13C‐NMR. analysis of heyneanine determined its C(19) configuration and a similar study of epiheyneanine proved its structure.

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