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A. Hofmann

2 papers in the library · 294 citations · publishing 1959

Papers

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Psilocybin und Psilocin, zwei psychotrope Wirkstoffe aus mexikanischen Rauschpilzen

Helvetica Chimica Acta 1959 A. Hofmann, Richard R. Heim, André Brack et al. 225 citations

Abstract The psychotropically active principles of the Mexican hallucinogenic fungus Psilocybe maxicana H EIM have been isolated and obtained in crystalline form. The two new substances, which have been called psilocybin and psilocin , are present in the fruit bodies, the artificially cultivated mycelium and in the sclerotia. The dried mushroom contains 0.2 to 0.4 per cent psilocybin. Psilocin...

Abwandlungsprodukte von Psilocybin und Psilocin. 2. Mitteilung über synthetische Indolverbindungen

Helvetica Chimica Acta 1959 F. Troxler, Frauke Seemann, A. Hofmann 69 citations

Abstract Various modifications were made in the molecular structure of the natural psychotropic substances psilocybin (I) and psilocin (11) to obtain an insight into the relationship between structure and psychotropic action of this group of substances. A description is given of the synthesis and properties of the position isomers of I and II with a phosphoryloxy or hydroxy group in position 5,...