Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans.
PLoS Biology October 1, 2025 Michele Angelo Colombo, Jacopo Favaro, Ezequiel Mikulan et al. 7 citations
Hemispherotomy is a neurosurgical procedure for treating refractory epilepsy, which entails disconnecting a significant portion of the cortex, potentially encompassing an entire hemisphere, from its cortical and subcortical connections. While this intervention prevents the spread of seizures, it raises important questions. Given the complete isolation from sensory-motor pathways, it remains...