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Michele Angelo Colombo

3 papers in the library · 64 citations · publishing 2023-2025

Papers

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Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans.

PLoS Biology October 1, 2025 Michele Angelo Colombo, Jacopo Favaro, Ezequiel Mikulan et al. 7 citations

Hemispherotomy is a neurosurgical procedure for treating refractory epilepsy, which entails disconnecting a significant portion of the cortex, potentially encompassing an entire hemisphere, from its cortical and subcortical connections. While this intervention prevents the spread of seizures, it raises important questions. Given the complete isolation from sensory-motor pathways, it remains...

Critical dynamics in spontaneous EEG predict anesthetic-induced loss of consciousness and perturbational complexity.

Communications Biology August 5, 2024 Charlotte Maschke, Jordan O'Byrne, Michele Angelo Colombo et al. 50 citations

Consciousness has been proposed to be supported by electrophysiological patterns poised at criticality, a dynamical regime which exhibits adaptive computational properties, maximally complex patterns and divergent sensitivity to perturbation. Here, we investigate dynamical properties of the resting-state electroencephalogram (EEG) of healthy subjects undergoing general anesthesia with propofol,...

Criticality of resting-state EEG predicts perturbational complexity and level of consciousness during anesthesia.

bioRxiv : the preprint server for biology October 31, 2023 Charlotte Maschke, Jordan O'Byrne, Michele Angelo Colombo et al. 7 citations preprint

Consciousness has been proposed to be supported by electrophysiological patterns poised at criticality, a dynamical regime which exhibits adaptive computational properties, maximally complex patterns and divergent sensitivity to perturbation. Here, we investigated dynamical properties of the resting-state electroencephalogram of healthy subjects undergoing general anesthesia with propofol,...