Effects on homeostasis of 5-hydroxytryptamine, lysergic acid diethylamide and 2-brom-d-lysergic acid
American Journal of Physiology-Legacy Content December 1, 1959 J. Paul Mcneill, John K. Hampton 3 citations
Rats were injected intramuscularly with 5-HT or LSD and intravenously with 5-HT, LSD, BOL or equimolar concentrations of 5-HT + LSD or 5-HT + BOL. Appropriate saline controls were included. They were then exposed to a standard amount of Noble-Collip trauma. Animals receiving 5-HT i.m. showed a significant multiphasic mortality curve after trauma depending on dose of drug. With small doses,...