European Archives of Psychiatry and Clinical Neuroscience
May 19, 2026
Mi Yang, Yuzheng Ma, Jialong Huang et al.
The neurobiological mechanisms underlying the therapeutic effects of meditation therapy in patients with schizophrenia remain poorly understood, therefore, we aim to investigate the relationship between clinical symptoms and the structural changes in brain gray matter in a meditation intervention trial. Han inpatients with schizophrenia admitted to the Shanghai First Civil Affairs Mental Health...
medRxiv
November 20, 2025
Qing Wang, Lizhao Du, Jialing Sheng et al.
preprint
Whether and how meditation benefits severe psychosis over clinically meaningful timescales remains unclear. We embedded longitudinal neuroimaging in an eight-month, parallel group randomized clinical trial (ChiCTR1800014913) of male inpatients (n=64) with schizophrenia receiving daily clinician-guided meditation plus rehabilitation versus rehabilitation alone. Meditation improved the symptoms...
Frontiers in Psychiatry
2025
Di Kong, Shoukang Zou, Yanqing Huang et al.
Meditation combined with antipsychotic medication can effectively improve the clinical symptoms and prognosis of patients with schizophrenia, but its underlying neural circuit mechanism is not clear. Many previous studies have shown that the symptoms of schizophrenia are related to dysfunction of the insula. We aimed to explore the neural circuitry mechanisms associated with insular dynamic...
Cerebral Cortex
July 1, 2024
Yupeng Han, Lizhao Du, Qiyun Huang et al.
Meditation, mental training that aims to improve one's ability to regulate their cognition, has been widely applied in clinical medicine. However, the mechanism by which meditation affects brain activity is still unclear. To explore this question, electroencephalogram data were recorded in 20 long-term meditators and 20 nonmeditators during 2 high-level cognitive tasks (meditation and mental...
Psychiatry and Clinical Neurosciences
April 1, 2024
Ting Xue, Jialing Sheng, Hui Gao et al.
5 citations
This study investigated the impact of an 8-month daily-guided intensive meditation-based intervention (iMI) on persistent hallucinations/delusions and health-related quality of life (QoL) in male inpatients with schizophrenia with treatment-refractory hallucinations and delusions (TRHDs). A randomized controlled trial assigned 64 male inpatients with schizophrenia and TRHD equally to an 8-month...
General Psychiatry
July 13, 2020
Hui Shen, Meijuan Chen, Donghong Cui
43 citations
In recent years, research on meditation as an important alternative therapy has developed rapidly and been widely applied in clinical medicine. Mechanism studies of meditation have also developed progressively, showing that meditation has great impact on brain structure and function, and epigenetic and telomere regulation. In line with this, the application of meditation has gradually been...
Cerebral cortex (New York, N.Y. : 1991)
March 21, 2020
Haiteng Jiang, Bin He, Xiaoli Guo et al.
40 citations
Despite accumulating evidence suggesting improvement in one's well-being as a result of meditation, little is known about if or how the brain and the periphery interact to produce these behavioral and mental changes. We hypothesize that meditation reflects changes in the neural representations of visceral activity, such as cardiac behavior, and investigated the integration of neural and...