Eight-month intensive meditation-based intervention improves refractory hallucinations and delusions and quality of life in male inpatients with schizophrenia: a randomized controlled trial.
Psychiatry and Clinical Neurosciences April 1, 2024 Ting Xue, Jialing Sheng, Hui Gao et al. 5 citations
An 8-month daily guided intensive meditation-based intervention (iMI) added to a general rehabilitation program reduced persistent hallucinations and delusions and improved health-related quality of life in male inpatients with treatment-refractory schizophrenia. In a randomized trial of 64 participants, those receiving iMI showed significantly greater reductions in Positive and Negative Syndrome Scale total scores, positive symptoms, and hallucination/delusion items at both 3 and 8 months compared with rehabilitation alone. Treatment response rates (at least 25% reduction) for these measures were higher in the iMI group at 8 months. The iMI group also reported better physical activity and mindfulness skills. Longer iMI duration produced stronger benefits.