Consciousness ignition is usually described as a whole-brain integration process after information enters the global workspace. But this paper offers a bold guess from the perspective of a limited-resource system: consciousness ignition may not just be an information-entry process, but a dynamic computational resource scheduling process. This paper argues that although the brain possesses...
Here, we present a large-scale, multi-center dataset of combined magnetoencephalographic (MEG) and electroencephalographic (EEG) recordings, along with eye-tracking data and high-resolution structural MRI (T1); complementing with iEEG and fMRI datasets that are shared in accompanying data papers. The data was obtained through an adversarial collaboration between advocates of two neuroscientific...
Different theories explain how subjective experience arises from brain activity1,2. These theories have independently accrued evidence, but have not been directly compared3. Here we present an open science adversarial collaboration directly juxtaposing integrated information theory (IIT)4,5 and global neuronal workspace theory (GNWT)6-10 via a theory-neutral consortium11-13. The theory...
Cautious reporting choices can artificially enhance how well analyses of brain activity reflect conscious and unconscious experiences, making distinguishing between the two more challenging.
Different theories explain how subjective experience arises from brain activity1,2. These theories have independently accrued evidence, yet, confirmation bias and dependence on design choices hamper progress in the field3. Here, we present an open science adversarial collaboration which directly juxtaposes Integrated Information Theory (IIT)4,5 and Global Neuronal Workspace Theory (GNWT)6–10,...
The relationship between conscious experience and brain activity has intrigued scientists and philosophers for centuries. In the last decades, several theories have suggested different accounts for these relationships. These theories have developed in parallel, with little to no cross-talk among them. To advance research on consciousness, we established an adversarial collaboration between...
PURPOSE OF REVIEW To explore the convergent downstream pathways of ketamine and rapastinel and drive further development of identification for following generational rapid-acting antidepressants in the synaptic process. RECENT FINDINGS Ketamine is an NMDAR antagonist and is proven effective in depression for the rapid and sustained antidepressant response, while rapastinel is an NMDAR positive...