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Michael R. Irwin

6 papers in the library · 608 citations · publishing 2009-2021

Papers

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A mindfulness meditation mobile app improves depression and anxiety in adults with sleep disturbance: Analysis from a randomized controlled trial

General Hospital Psychiatry September 11, 2021 Jennifer Huberty, Megan E. Puzia, Jeni Green et al. 76 citations

OBJECTIVE: The objective of this study was to 1) determine the effects of a meditation app on depression and anxiety in adults with sleep disturbance, and 2) explore the potential mediating effects of fatigue, daytime sleepiness, and pre-sleep arousal on the relationship between use of the meditation app and changes in depression and anxiety. METHODS: Participants were 239 adults with elevated...

Depression treatment response to ketamine: sex-specific role of interleukin-8, but not other inflammatory markers

Translational Psychiatry March 21, 2021 Jennifer L. Kruse, Megha M Vasavada, Richard Olmstead et al. 47 citations

Abstract Inflammation plays a role in depression pathophysiology and treatment response, with effects varying by sex and therapeutic modality. Lower levels of interleukin(IL)-8 predict depression response to antidepressant medication and to electroconvulsive therapy (ECT), although ECT effects are specific to females. Whether IL-8 predicts depression response to ketamine and in a sex-specific...

Can a meditation app help my sleep? A cross-sectional survey of Calm users.

PLoS One 2021 Jennifer Huberty, Megan E. Puzia, Linda Larkey et al.

Use of mindfulness mobile apps has become popular, however, there is little information about subscribers' perceptions of app content and its impact on sleep and mental health. The purpose of this study was to survey subscribers to Calm, a popular mindfulness meditation app, to explore perceived improvements in sleep and mental health, evaluate what components of the app were associated with...

Mindfulness meditation and improvement in depressive symptoms among Spanish- and English speaking adults: A randomized, controlled, comparative efficacy trial.

PLoS One July 15, 2019 Eric López Maya, Richard Olmstead, Michael R. Irwin

ObjectiveLatino immigrants experience acculturative stress and increased depression risk. Mindfulness meditation improves depressive symptoms, yet the vast majority of research has focused on English speaking populations.MethodsIn this randomized clinical trial with 2 parallel treatment groups, adults with moderate levels of perceived stress (n = 76) were recruited from the Los Angeles...

Mindfulness Meditation and Improvement in Sleep Quality and Daytime Impairment Among Older Adults With Sleep Disturbances

JAMA Internal Medicine February 16, 2015 David S. Black, Gillian A. O’Reilly, Richard Olmstead et al. 485 citations

IMPORTANCE: Sleep disturbances are most prevalent among older adults and often go untreated. Treatment options for sleep disturbances remain limited, and there is a need for community-accessible programs that can improve sleep. OBJECTIVE: To determine the efficacy of a mind-body medicine intervention, called mindfulness meditation, to promote sleep quality in older adults with moderate sleep...

Mindfulness meditation training effects on CD4+ T lymphocytes in HIV-1 infected adults: a small randomized controlled trial.

Brain, behavior, and immunity February 2009 J David Creswell, Hector F Myers, Steven W Cole et al.

Mindfulness meditation training has stress reduction benefits in various patient populations, but its effects on biological markers of HIV-1 progression are unknown. The present study tested the efficacy of an 8-week Mindfulness-based stress reduction (MBSR) meditation program compared to a 1-day control seminar on CD4+ T lymphocyte counts in stressed HIV infected adults. A single-blind...