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Herbert H. Seltman

1 paper in the library · 10 citations · publishing 1992

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A new approach to tritium labelling; the synthesis of [3H]ibogaine

Journal of the Chemical Society Chemical Communications 1992 Herbert H. Seltman, Denise F. Odear, F. Ivy Carroll et al. 10 citations

Tritium labelled ibogaine, for pharmacological studies as an anti-addiction treatment for cocaine abuse, is prepared by a new method for the tritiation of aryl compounds involving ortho metallation followed by facile reduction of the carbon–metal bond.