Neuroscience
January 17, 2022
Ricky Chow, Rahel Rabi, Shahier Paracha et al.
23 citations
Aging is associated with altered brain connectivity within the default mode network (DMN). Although research using functional magnetic resonance imaging has quantified age-related alterations in functional connectivity within this network during resting state, it is less clear how this may be reflected in electrophysiological measures, and how this relates to cognitive performance in older...
Journal of Magnetic Resonance Imaging
April 17, 2015
Ekaterina Tchistiakova, David Crane, David J. Mikulis et al.
20 citations
PURPOSE: White matter hyperintensities (WMH) are prevalent among older adults and are often associated with cognitive decline and increased risk of stroke and dementia. Vascular risk factors (VRFs) are linked to WMH, yet the impact of multiple VRFs on gray matter function is still unclear. The goal of this study was to test for associations between the number of VRFs and cerebrovascular...
Pharmacology, biochemistry, and behavior
April 2010
Sarah M Turgeon, Nicole Anderson, Kerry O'Loughlin
Previous research in our laboratory indicates that the psychotomimetic drug phencyclidine (PCP) reduces voluntary sucrose consumption in male rats, potentially modeling the schizophrenic symptom of anhedonia. Given reports from the clinical literature that schizophrenia has a later age of onset and more favorable outcome in females, PCP might be expected to have sexually dimorphic effects in...
Clinical Psychology & Psychotherapy
November 1, 2007
Nicole D. Anderson, Mark A. Lau, Zindel V. Segal et al.
326 citations
Abstract This study was designed to test the hypothesis that mindfulness involves sustained attention, attention switching, inhibition of elaborative processing and non‐directed attention. Healthy adults were tested before and after random assignment to an 8‐week Mindfulness‐Based Stress Reduction (MBSR) course ( n = 39) or a wait‐list control ( n = 33). Testing included measures of sustained...
Journal of Clinical Psychology
2006
Mark A. Lau, Scott R. Bishop, Zindel V. Segal et al.
1,462 citations
In this study, the authors both developed and validated a self-report mindfulness measure, the Toronto Mindfulness Scale (TMS). In Study 1, participants were individuals with and without meditation experience. Results showed good internal consistency and two factors, Curiosity and Decentering. Most of the expected relationships with other constructs were as expected. The TMS scores increased...
Clinical Psychology Science and Practice
2004
Scott R. Bishop, Mark A. Lau, Shauna L. Shapiro et al.
6,266 citations
There has been substantial interest in mindfulness as an approach to reduce cognitive vulnerability to stress and emotional distress in recent years. However, thus far mindfulness has not been defined operationally. This paper describes the results of recent meetings held to establish a consensus on mindfulness and to develop conjointly a testable operational definition. We propose a...