Lysergic Acid Diethylamide: Sensitive Neuronal Units in the Midbrain Raphe
Science August 16, 1968 George K. Aghajanian, Warren E. Foote, Michael H. Sheard 406 citations
Units in areas of the midbrain rich in neurons containing serotonin respond to parenteral injections of d-lysergic acid diethylamide by a reversible cessation of spontaneous activity. The dose required is at or below threshold for gross behavioral effects. An inhibition of neurons containing serotonin after administration of d-lysergic acid diethylamide could account for the decreased...