Mutation Research/Reviews in Genetic Toxicology
1977
Maimon M. Cohen, Yosef Shiloh
28 citations
The acute and the chronic psychotomimetic potentials of the hallucinogen lysergic acid diethylamide (LSD-25) have been recognized for almost 40 years. That additional types of the biological effects should have come under scrutiny was directly attributable to widespread use and abuse of this drug on a world-wide basis. Although "genetic toxicology" encompasses a broad spectrum of disciplines,...
New England Journal of Medicine
November 16, 1967
Maimon M. Cohen, Kurt Hirschhorn, William A. Frosch
150 citations
THE induction of chromosomal aberrations by exogenous agents, such as viruses, radiation and chemicals, is an area of active cytogenetic investigation.1 Recently, the psychotomimetic hallucinogen, lysergic acid diethylamide (LSD-25), has been added to the list of chemicals capable of causing abnormalities in the chromosomes of human leukocytes.2 , 3 Such preliminary studies report the in vitro...
Annals of Internal Medicine
November 1, 1967
Kurt Hirschhorn, Maimon M. Cohen
2 citations
Editorials1 November 1967Nonpsychic Effects of Lysergic Acid DiethylamideKURT HIRSCHHORN, M.D., MAIMON M. COHEN, PH.D.KURT HIRSCHHORN, M.D.Search for more papers by this author, MAIMON M. COHEN, PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-67-5-1109 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack...
Science
March 17, 1967
Maimon M. Cohen, Michelle J. Marinello, Nathan Back
199 citations
Addition of lysergic acid diethylamide to cultured human leukocytes resulted in a marked increase of chromosomal abnormalities. The distribution of chromosome breaks deviated significantly from random, with an accumulation of aberrations in chromosome No. 1. Cytogenetic investigation of a patient extensively treated with this drug over a 4-year period for paranoid schizophrenia showed a similar...