Therapeutic Advances in Psychopharmacology
October 1, 2026
Xin Yang, Shuping Fang, Kejia Hu et al.
Background: Psychedelics, including classic psychedelics, 3,4-methylenedioxymethamphetamine (MDMA), and ketamine, are increasingly investigated for psychiatric disorders, but their effects on sleep remain unclear. Objectives: To systematically evaluate the effects of these interventions on subjective and objective sleep outcomes and summarize sleep-related adverse events. Design: A systematic...
Nature and Science of Sleep
September 1, 2026
Jiaxue Huang, Meiou Wang, Wenxin Bao et al.
Objectives: This study conducted a systematic evaluation of polysomnographic differences between individuals with nightmares and healthy controls. Methods: Electronic searches of All EBM databases, EMBASE, Web of Science, and MEDLINE identified 14 eligible case-control studies; seven studies involving 112 individuals with nightmares and 112 controls were included in meta-analysis. Results: The...
Nature
January 28, 2026
Zheng Xu, Hongshuang Wang, Jingjing Yu et al.
5 citations
Psychedelics are undergoing a renaissance as potential therapy for psychiatric disorders, with more than 200 clinical trials being studied across several countries1-3. However, the precise mechanisms by which these drugs bring about benefits and the potential clinical risks are not yet fully understood. The serotonin 2A receptor (5-HT2AR) was reported to be a Gq-coupled receptor and the primary...
The International Journal of Neuropsychopharmacology
May 24, 2023
Yuru Nie, Ye Zhang, Rong Ren et al.
1 citation
Trauma-related nightmares (TRN) are a reexperiencing of previous traumas that happened in real life or a dream sequence initially triggered by trauma that leads to recurrent emotional dreaming about the trauma. TRN, one of the most common symptoms in posttraumatic stress disorder (PTSD), are disturbing mental experiences that generally occur during rapid eye movement (REM) sleep and often...