Roscoe O. Brady

THE DISTRIBUTION AND METABOLISM OF LYSERGIC ACID DIETHYLAMIDE

Annals of the New York Academy of Sciences March 1, 1957 Julius Axelrod, Roscoe O. Brady, Bernhard Witkop et al. 154 citations

Late in the 1950s, Axelrod became interested in the distribution, excretion, metabolization and rate of "biotransformation" of lysergic acid diethylamide (LSD) by the body. In this first of several articles on the narcotic drug, he detailed the subcellular processes involved in the transformation of LSD, determined the order of concentrations of the drug in various tissues, determined that it...