American Journal of Psychiatry
April 1, 1969
Leo E. Hollister, Jack Shelton, George Krieger
104 citations
Seventy-two alcoholic patients were admitted to a controlled comparison of LSD and dextroamphetamine as treatments. In the context of little associated psychotherapeutic intervention, LSD produced slightly better results early, but after six months the results were alike for both treatment groups. Controlled studies of such treatments are not only possible but mandatory, the authors conclude,...
Clinical Pharmacology & Therapeutics
November 1, 1968
Leo E. Hollister, R. K. Richards, H. K. Gillespie
195 citations
A synthetic isomer of tetrahydrocannabinol (1‐Δ'‐3,4‐transtetrahydrocannabinol), believed to be identical to the most active naturally occurring THC, was compared with a semisynthetic THC‐like compound, synhexyl. Sixteen volunteer subiects received THC in doses ranging from 341 to 946 p.g per kilo gram (median 581). Thirteen subjects received synhexyl in doses ranging from 633 to 2,666 µg per...
Science
November 3, 1967
Solomon H. Snyder, Louis A. Faillace, Leo E. Hollister
146 citations
We have assessed the effects in normal control volunteers of 2,5-dimethoxy-4-methyl-amphetamine, the chemical present in the hallucinogenic drug STP, in two independent trials. In low doses, this compound produces a mild euphoria. Doses greater than 3 milligrams may cause pronounced hallucinogenic effects lasting about 8 hours and similar to those produced by hallucinogenic doses of lysergic...
The Journal of Nervous and Mental Disease
November 1, 1960
Leo E. Hollister, John J. Prusmack, James A. Paulsen et al.
40 citations
HOLLISTER, LEO E. M.D.; PRUSMACK, JOHN J. M.D.; PAULSEN, JAMES A. M.D.; ROSENQUIST, NORMA Author Information