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Trevor R. Norman

5 papers in the library · 83 citations · publishing 1988-2025

Papers

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The psychedelic renaissance: psilocybin, a breakthrough for treatment resistant depression?

Exploration of Neuroscience August 7, 2025 Trevor R. Norman 2 citations

Treatment resistant depression (TRD) is frequently encountered in clinical practice. The lack of response of the condition to conventional medications and augmentation strategies has spawned the search for novel treatment approaches. Psychedelic medications used in conjunction with intensive psychotherapy, so-called psychedelic-assisted psychotherapy (PAP), have been evaluated in a limited...

Psilocybin in neuropsychiatry: a review of its pharmacology, safety, and efficacy

CNS Spectrums July 11, 2022 Seetal Dodd, Trevor R. Norman, Harris A. Eyre et al. 61 citations

Abstract Psilocybin is a tryptamine alkaloid found in some mushrooms, especially those of the genus Psilocybe. Psilocybin has four metabolites including the pharmacologically active primary metabolite psilocin, which readily enters the systemic circulation. The psychoactive effects of psilocin are believed to arise due to the partial agonist effects at the 5HT2A receptor. Psilocin also binds to...

5-HT2A Agonists: A Novel Therapy for Functional Neurological Disorders?

The International Journal of Neuropsychopharmacology February 8, 2017 Alexander Bryson, Olivia Carter, Trevor R. Norman et al. 19 citations

Functional neurological disorders are frequently encountered in clinical practice. They have a poor prognosis and treatment options are limited. Their etiology is unknown, but leading theories propose a disturbance of somatic self-representation: the mind perceives dysfunction of a body region despite intact motor and sensory pathways. Central to this model is the concept of an abnormal...

Acute increases in night-time plasma melatonin levels following a period of meditation.

Biological Psychology May 1, 2000 G. Tooley, S. Armstrong, Trevor R. Norman et al.

To determine whether a period of meditation could influence melatonin levels, two groups of meditators were tested in a repeated measures design for changes in plasma melatonin levels at midnight. Experienced meditators practising either TM-Sidhi or another internationally well known form of yoga showed significantly higher plasma melatonin levels in the period immediately following meditation...