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Harris A. Eyre

1 paper in the library · 61 citations · publishing 2022

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Psilocybin in neuropsychiatry: a review of its pharmacology, safety, and efficacy

CNS Spectrums July 11, 2022 Seetal Dodd, Trevor R. Norman, Harris A. Eyre et al. 61 citations

Abstract Psilocybin is a tryptamine alkaloid found in some mushrooms, especially those of the genus Psilocybe. Psilocybin has four metabolites including the pharmacologically active primary metabolite psilocin, which readily enters the systemic circulation. The psychoactive effects of psilocin are believed to arise due to the partial agonist effects at the 5HT2A receptor. Psilocin also binds to...