A New Hallucinogen: 3,4,5-Trimethoxyphenyl-β-Aminopropane
Dwight I. Peretz, John Smythies, William C. Gibson
Journal of Mental Science April 1, 1955 DOI: 10.1192/bjp.101.423.317 (opens in new tab) via OpenAlex
Summary
AI-generated from the abstractTMA (3,4,5-Trimethoxyphenyl-β-aminopropane) shares a chemical structure with both amphetamine and mescaline. Because of this dual relationship, researchers anticipated that the compound might produce clinical effects combining features of both drugs. The study investigated whether TMA would indeed elicit a blend of amphetamine-like and mescaline-like responses in practice.
Study at a glance
| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Interventions | 3 4 5-Trimethoxyphenyl-β-aminopropane (TMA) |
| Topics | Mescaline |
| Keywords | Hallucinogen Amphetamine Psychology |
| Citations | 55 |
| Key finding | TMA is structurally related to both amphetamine and mescaline, raising the question of whether its clinical effects would combine characteristics of both drugs. |
Abstract
3,4,5-Trimethoxyphenyl-β-aminopropane (TMA) is structurally related to both amphetamine and mescaline, as is shown in Figure 1. Because of this structural relationship of TMA and amphetamine, methedrine, and mescaline, one could anticipate a clinical response to the compound which would represent certain phenomena characteristic of each of these drugs. This presented an intriguing problem as to whether or not, in actuality, this would be the case.