Forensic Science International
June 1, 2025
Ana Y. Simão, P Y Tokuyama, G Zampieri et al.
1 citation
In this study, over 900 hair samples from individuals using drugs of abuse in São Paulo and Rio Grande do Sul, Brazil were analysed for classical drugs and new psychoactive substances (NPS) in hair samples. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods were developed for the detection of some drugs (25B-NBOMe, 25C-NBOMe, 25E-NBOH, 2C-C, 2C-I, 3,4-MDPHP, 3-MeO-PCP,...
Phytochemical analysis : PCA
August 1, 2024
Joana Gonçalves, Tiago Rosado, Mário Barroso et al.
2 citations
Ayahuasca is a psychoactive drink originally consumed by indigenous people of the Amazon. The lack of regulation of this drink leads to uncontrolled consumption, and it is often consumed in religious contexts. The aim of this work is to compare three miniaturised extraction techniques for extracting the main ayahuasca compounds from beverages. Three sample pretreatment techniques were evaluated...
Micromachines
July 30, 2024
Rodrigo Pelixo, Mário Barroso, Eugenia Gallardo et al.
1 citation
Arylcyclohexylamine (ACH) compounds represent a predominant faction within new psychoactive substances. Due to their powerful dissociative effects, they are used in recreational contexts but also in situations of drug-facilitated sexual assault, and therefore, they are a constant target of analysis by forensic experts. In recent years, their consumption has been notably high, especially the use...
Life
November 8, 2023
Bruno Pires, Luana M. Rosendo, Ana Teresa Brinca et al.
15 citations
This review delves into the therapeutic applications of amphetamine-type stimulants such as lisdexamphetamine dimesylate, mixed amphetamine salts, 3,4-methylenedioxymethamphetamine (MDMA), dextroamphetamine, and phentermine. These compounds have been investigated for their potential in treating a range of psychiatric disorders, including attention deficit hyperactivity disorder (ADHD), drug...
Molecules
February 26, 2021
Ana Y. Simão, Joana Gonçalves, Ana Gradillas et al.
correction
This paper [...]
Molecules
November 28, 2020
Ana Y. Simão, Joana Gonçalves, Ana Gradillas et al.
19 citations
Ayahuasca is a beverage consumed at shamanic ceremonies and currently has gained popularity on recreational scenarios. It contains beta-carboline alkaloids and N,N-dimethyltryptamine, which possesses hallucinogenic effects. Only a few studies have elicited the psychoactive effects and the dose of such compounds on neurological dopaminergic cells or animals. In this work, we aimed to study the...
Biomedicines
September 5, 2020
Ana Sofia Vargas, Ângelo Luís, Mário Barroso et al.
121 citations
Psilocybin is a naturally occurring tryptamine known for its psychedelic properties. Recent research indicates that psilocybin may constitute a valid approach to treat depression and anxiety associated to life-threatening diseases. The aim of this work was to perform a systematic review with meta-analysis of clinical trials to assess the therapeutic effects and safety of psilocybin on those...
Medicines
October 18, 2019
Ana Y. Simão, Joana Gonçalves, Ana Paula Duarte et al.
36 citations
Ayahuasca is a psychoactive beverage prepared traditionally from a mixture of the leaves and stems of Psychotria viridis and Banisteriopsis caapi, respectively, being originally consumed by indigenous Amazonian tribes for ritual and medicinal purposes. Over the years, its use has spread to other populations as a means to personal growth and spiritual connection. Also, the recreational use of...