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José Restolho

5 papers in the library · 55 citations · publishing 2020-2024

Papers

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Comparative study of sample preparation procedures to determine the main compounds in ayahuasca beverages by QuEChERS and high-performance liquid chromatography analysis.

Phytochemical analysis : PCA August 1, 2024 Joana Gonçalves, Tiago Rosado, Mário Barroso et al. 2 citations

Ayahuasca is a psychoactive drink originally consumed by indigenous people of the Amazon. The lack of regulation of this drink leads to uncontrolled consumption, and it is often consumed in religious contexts. The aim of this work is to compare three miniaturised extraction techniques for extracting the main ayahuasca compounds from beverages. Three sample pretreatment techniques were evaluated...

In Vitro Study of the Bioavailability and Bioaccessibility of the Main Compounds Present in Ayahuasca Beverages

Molecules September 13, 2021 Joana Gonçalves, Miguel Castilho, Tiago Rosado et al. 9 citations

Ayahuasca is a psychoactive beverage that contains the psychoactive compound N,N-dimethyltryptamine and β-carboline alkaloids. This study aims at determining in vitro the bioavailability and bioaccessibility of the main compounds present in decoctions of four individual plants, in a commercial mixture and in four mixtures of two individual plants used in the preparation of Ayahuasca. The...

Evaluation of the Cytotoxicity of Ayahuasca Beverages

Molecules November 28, 2020 Ana Y. Simão, Joana Gonçalves, Ana Gradillas et al. 19 citations

Ayahuasca is a beverage consumed at shamanic ceremonies and currently has gained popularity on recreational scenarios. It contains beta-carboline alkaloids and N,N-dimethyltryptamine, which possesses hallucinogenic effects. Only a few studies have elicited the psychoactive effects and the dose of such compounds on neurological dopaminergic cells or animals. In this work, we aimed to study the...

Ayahuasca Beverages: Phytochemical Analysis and Biological Properties

Antibiotics October 24, 2020 Joana Gonçalves, Ângelo Luís, Ana Gradillas et al. 25 citations

Ayahuasca is a psychoactive beverage, originally consumed by indigenous Amazon tribes, of which consumption has been increasing worldwide. The aim of this study was to evaluate the phytochemical profile, as well as the antioxidant, anti-inflammatory and antimicrobial properties of decoctions of four individual plants, a commercial mixture and four mixtures of two individual plants used in the...