July 31, 2026
Samantha Lee Treasure, Alexander de Foe, Sam Gandy et al.
The primary aim of this study is to explore the demographic, experiential, and phenomenological variables of entity encounters during out-of-body experiences (OBEs) through an online survey shared with adults.
Frontiers in Conservation Science
September 29, 2025
Anna O. Ermakova, Sam Gandy
Psychedelics have a profound potential to catalyze psychological transformation and support traditional cultures and ways of life. However, many naturally occurring psychoactive plants and animals are facing threats from climate change, habitat loss and other anthropogenic pressures like overharvesting. In this narrative review we examine the conservation issues pertaining to some of the most...
Drug Science Policy and Law
2024
Simon Ruffell, Sam Gandy, WaiFung Tsang et al.
10 citations
Indigenous Amazonian shamanic ayahuasca practice is embedded in a nature-based context and is employed as an ecological mediating agent and in collective environmental decision-making processes by some of the groups that use it. Phenomenologically, the ayahuasca experience is often rich in nature-based themes and content, and its usage has been associated with eliciting shifts in perspectives...
PCN reports : psychiatry and clinical neurosciences
December 1, 2023
Simon Ruffell, Max Crosland-Wood, Rob Palmer et al.
37 citations
Ayahuasca is a psychedelic plant brew originating from the Amazon rainforest. It is formed from two basic components, the Banisteriopsis caapi vine and a plant containing the potent psychedelic dimethyltryptamine (DMT), usually Psychotria viridis. Here we review the history of ayahuasca and describe recent work on its pharmacology, phenomenological responses, and clinical applications. There...
Psychoactives
May 25, 2023
Alexander Irvine, David Luke, Freya Harrild et al.
22 citations
Objective: To explore the perceived influence of psychedelic experiences on participants’ relationship with the natural world. Method: A total of 272 participants reporting previous use of psychedelics completed free-text response requests via an online survey. Thematic analysis was used to explore group participant responses. Results: Participants who described a pre-existing relationship with...
Journal of Psychopharmacology
2023
Matthias Forstmann, Christina Sagioglou, Alexander Irvine et al.
18 citations
Background: Past research reports a positive relationship between experience with classic serotonergic psychedelics and nature relatedness (NR). However, these studies typically do not distinguish between different psychedelic compounds, which have a unique psychopharmacology and may be used in specific contexts and with different intentions. Likewise, it is not clear whether these findings can...
Psychopharmacology
August 8, 2022
Rosalind Watts, Hannes Kettner, Dana Geerts et al.
159 citations
Abstract Rationale A general feeling of disconnection has been associated with mental and emotional suffering. Improvements to a sense of connectedness to self, others and the wider world have been reported by participants in clinical trials of psychedelic therapy. Such accounts have led us to a definition of the psychological construct of ‘connectedness’ as ‘a state of feeling connected to...
Journal of Psychedelic Studies
March 22, 2022
Sam Gandy
19 citations
Abstract Mystical experiences are often described as being among the most profound and meaningful events of a person’s life. Their occurrence, while a normal but uncommon phenomenon, is reliably occasioned by psychedelic substances under the appropriate conditions, although care is needed around the context of usage to help ensure safe and beneficial experiences. The occurrence of mystical...
Drug Science Policy and Law
2022
Sam Gandy, Valerie Bonnelle, Edward Jacobs et al.
26 citations
Creativity, that is the creation of ideas or objects considered both novel and valuable, is among the most important and highly valued of human traits, and a fundamental aspect of the sciences. Dreams and hypnagogic states have been highly influential in promoting scientific creativity and insight, contributing to some important scientific breakthroughs. Phenomenologically, the latter states of...
Health Psychol Open
July 1, 2020
Sam Gandy, Matthias Forstmann, Robin Lester Carhart-Harris et al.
64 citations
The potential synergistic effects between psychedelic administration and nature contact for the improvement of mental health.
International Journal of Environmental Research and Public Health
December 16, 2019
Hannes Kettner, Sam Gandy, Eline Haijen et al.
159 citations
(1) Background: There appears to be a growing disconnection between humans and their natural environments which has been linked to poor mental health and ecological destruction. Previous research suggests that individual levels of nature relatedness can be increased through the use of classical psychedelic compounds, although a causal link between psychedelic use and nature relatedness has not...
Journal of Psychedelic Studies
September 1, 2019
Sam Gandy
44 citations
We are in the midst of a psychedelic research renaissance. With research examining the efficacy of psychedelics as a treatment for a range of mental health indications still in its early stages, there is an increasing body of research to show that careful use of psychedelics can yield a variety of benefits in “healthy normals” and so lead to “the betterment of well people.” Psychedelics have...
Psychiatry Research
April 4, 2018
Alba Franquesa, Alberto Sainz-Cort, Sam Gandy et al.
58 citations
Ayahuasca is a psychedelic decoction originating from Amazonia. The ayahuasca-induced introspective experience has been shown to have potential benefits in the treatment of several pathologies, to protect mental health and to improve neuropsychological functions and creativity, and boost mindfulness. The underlying psychological processes related to the use of ayahuasca in a psychotherapeutic...
Human Psychopharmacology
September 1, 2016
José Carlos Bouso, Eduardo José Pedrero-Pérez, Sam Gandy et al.
48 citations
In the present study we explored the psychometric properties of three widely used questionnaires to assess the subjective effects of hallucinogens: the Hallucinogen Rating Scale (HRS), the Mystical Experience Questionnaire (MEQ), and the Addiction Research Center Inventory (ARCI). These three questionnaires were administered to a sample of 158 subjects (100 men) after taking ayahuasca, a...